• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

锂盐对突触体和肾脏匀浆脂质过氧化活性的影响。

Effects of lithium salts on lipid peroxidation activity of synaptosomes and kidney homogenates.

作者信息

Sawas A H, Gilbert J C, Watson M E

出版信息

Arch Int Pharmacodyn Ther. 1986 Jun;281(2):192-7.

PMID:3753101
Abstract

Lithium carbonate increased the lipid peroxidation while lithium sulphate and lithium chloride had no significant effects on lipid peroxidation activity of rat cerebral cortex synaptosomes and kidney homogenates. However, lithium chloride plus sodium carbonate significantly increased the lipid peroxidation activity of kidney homogenates. It is concluded that accompanying anions of lithium salts might play a major role in the increase of lipid peroxidation of both synaptosomes and kidney homogenates.

摘要

碳酸锂增加了脂质过氧化作用,而硫酸锂和氯化锂对大鼠大脑皮质突触体和肾匀浆的脂质过氧化活性没有显著影响。然而,氯化锂加碳酸钠显著增加了肾匀浆的脂质过氧化活性。得出的结论是,锂盐的伴随阴离子可能在突触体和肾匀浆脂质过氧化增加中起主要作用。

相似文献

1
Effects of lithium salts on lipid peroxidation activity of synaptosomes and kidney homogenates.锂盐对突触体和肾脏匀浆脂质过氧化活性的影响。
Arch Int Pharmacodyn Ther. 1986 Jun;281(2):192-7.
2
Lipid peroxidation as a possible mechanism for the neurotoxic and nephrotoxic effects of a combination of lithium carbonate and haloperidol.脂质过氧化作为碳酸锂和氟哌啶醇联用产生神经毒性和肾毒性作用的一种可能机制。
Arch Int Pharmacodyn Ther. 1985 Aug;276(2):301-12.
3
ATPase activities and lipid peroxidation in rat cerebral cortex synaptosomes.
Arch Int Pharmacodyn Ther. 1983 Jun;263(2):189-96.
4
Possible mechanism of inhibition by lipid peroxidation of ATPase activities of rat cerebral cortex synaptosomes.脂质过氧化抑制大鼠大脑皮质突触体ATP酶活性的可能机制。
Arch Int Pharmacodyn Ther. 1984 May;269(1):4-11.
5
Effects of lipid peroxidation on neurotransmitters uptake by rat synaptosomes.脂质过氧化对大鼠突触体摄取神经递质的影响。
Pol J Pharmacol Pharm. 1985 May-Jun;37(3):325-31.
6
[The effect of starvation of lipid peroxidation in synaptosomal and mitochondrial factions of various brain structures].
Vopr Med Khim. 1994 Mar-Apr;40(2):34-7.
7
[Mechanism of the stabilization of synaptosomes with alpha-tocopherol during activation of lipid peroxidation].[在脂质过氧化激活过程中α-生育酚对突触体的稳定作用机制]
Biokhimiia. 1986 Mar;51(3):472-7.
8
[Lipid peroxidation by rat brain synaptosomes in sleep disorders].
Fiziol Zh SSSR Im I M Sechenova. 1986 Aug;72(8):1065-8.
9
[Mechanisms of biomembrane stabilization with alpha-tocopherol. The role of the isoprenoid chain in the inhibition of lipid peroxidation].[α-生育酚对生物膜的稳定作用机制。类异戊二烯链在抑制脂质过氧化中的作用]
Dokl Akad Nauk SSSR. 1987;295(3):728-31.
10
Ethanol induced changes in lipid peroxidation and nonprotein sulfhydryl content. Different sensitivities in rat liver and kidney.乙醇诱导脂质过氧化和非蛋白巯基含量的变化。大鼠肝脏和肾脏的敏感性不同。
Res Commun Chem Pathol Pharmacol. 1985 Feb;47(2):203-9.

引用本文的文献

1
In Vitro and In Vivo Evidence on the Role of Mitochondrial Impairment as a Mechanism of Lithium-Induced Nephrotoxicity.锂致肾毒性的线粒体损伤机制的体外和体内证据。
Biol Trace Elem Res. 2021 May;199(5):1908-1918. doi: 10.1007/s12011-020-02302-9. Epub 2020 Jul 25.
2
Lipid peroxidation, antioxidant activities and stress protein (HSP72/73, GRP94) expression in kidney and liver of rats under lithium treatment.锂处理大鼠肾和肝组织中的脂质过氧化、抗氧化活性和应激蛋白(HSP72/73、GRP94)表达。
J Physiol Biochem. 2012 Mar;68(1):11-8. doi: 10.1007/s13105-011-0113-3. Epub 2011 Sep 27.
3
Lithium-induced renal toxicity in rats: protection by a novel antioxidant caffeic acid phenethyl ester.
锂诱导的大鼠肾毒性:新型抗氧化剂咖啡酸苯乙酯的保护作用
Mol Cell Biochem. 2005 Sep;277(1-2):109-15. doi: 10.1007/s11010-005-5426-5.