Zhou Yimin, Li Zongyang, Lao Kecheng, Wang Zixiu, Zhang Li, Dai Shiyou, Fan Xiao
College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, China.
Department of Osteoarticular and Sports Medicine, Qingdao Municipal Hospital, Qingdao, China.
Front Surg. 2023 Jul 18;10:1224559. doi: 10.3389/fsurg.2023.1224559. eCollection 2023.
This meta-analysis aimed to compare the relative safety and efficacy of cannulated compression screw (CCS) and femoral neck system (FNS) in treating patients with femoral neck fractures and to provide evidence-based medical evidence for FNS in treating femoral neck fractures.
PubMed, Embase, Cochrane, and China National Knowledge Infrastructure databases were searched to collect outcomes related to femoral neck fractures treated with FNS and CCS, including time to fracture healing, incidence of non-union, incidence of osteonecrosis of the femoral head, incidence of failure of internal fixation, rate of femoral neck shortening, Harris hip score, Barthel index, operative time, intraoperative blood loss, fluoroscopy frequency, and complications. A meta-analysis was performed using RevManv5.4 (The Cochrane Collaboration) and Stata v14.0 software.
This analysis included 21 studies involving 1,347 patients. The results showed that FNS was superior to CCS in terms of fracture healing time [mean difference (MD) = -0.75, 95% CI = (-1.04, -0.46), < 0.05], incidence of bone non-union [odds ratio (OR) = 0.53, 95% CI = (0.29, 0.98), = 0.04], incidence of osteonecrosis of the femoral head [OR = 0.49, 95% CI = (0.28, 0.86), = 0.01], incidence of internal fixation failure [OR = 0.30, 95% CI = (0.18, 0.52), < 0.05], rate of femoral neck shortening [OR = 0.38, 95% CI = (0.27, 0.54), > 0.05], Harris hip score [MD = 3.31, 95% CI = (1.99, 4.63), < 0.001], Barthel index [MD = 4.31, 95% CI = (3.02, 5.61), < 0.05], intraoperative bleeding [MD = 14.72, 95% CI = (8.52, 20.92), < 0.05], fluoroscopy frequency [OR = 0.53, 95% CI = (0.29, 0.98), = 0.04], and complications [OR = 0.31, 95% CI = (0.22, 0.45), < 0.05]. The difference between FNS and CCS in operative time was not statistically significant [MD = -2.41, 95% CI = (-6.88, 2.05), = 0.29].
FNS treatment of femoral neck fracture can shorten the fracture healing time; reduce the incidence and translucent rate of bone non-union, osteonecrosis of the femoral head, and internal fixation failure; reduce intraoperative blood loss and postoperative complications; and improve hip joint function and activity. We are confident in the findings that FNS, an effective and safe procedure for internal fixation of femoral neck fractures, is superior to CCS.
本荟萃分析旨在比较空心加压螺钉(CCS)和股骨颈系统(FNS)治疗股骨颈骨折患者的相对安全性和疗效,为FNS治疗股骨颈骨折提供循证医学依据。
检索PubMed、Embase、Cochrane和中国知网数据库,收集与FNS和CCS治疗股骨颈骨折相关的结果,包括骨折愈合时间、骨不连发生率、股骨头坏死发生率、内固定失败发生率、股骨颈缩短率、Harris髋关节评分、Barthel指数、手术时间、术中出血量、透视频率及并发症。使用RevManv5.4(Cochrane协作网)和Stata v14.0软件进行荟萃分析。
本分析纳入21项研究,共1347例患者。结果显示,FNS在骨折愈合时间[平均差(MD)=-0.75,95%可信区间(CI)=(-1.04,-0.46),P<0.05]、骨不连发生率[比值比(OR)=0.53,95%CI=(0.29,0.98),P=0.04]、股骨头坏死发生率[OR=0.49,95%CI=(0.28,0.86),P=0.01]、内固定失败发生率[OR=0.30,95%CI=(0.18,0.52),P<0.05]、股骨颈缩短率[OR=0.38,95%CI=(0.27,0.54),P>0.05]、Harris髋关节评分[MD=3.31,95%CI=(1.99,4.63),P<0.001]、Barthel指数[MD=4.31,95%CI=(3.02,5.61),P<0.05]、术中出血量[MD=14.72,95%CI=(8.52,20.92),P<0.05]、透视频率[OR=0.53,95%CI=(0.29,0.98),P=0.04]及并发症[OR=0.31,95%CI=(0.22,0.45),P<0.05]方面均优于CCS。FNS与CCS在手术时间上的差异无统计学意义[MD=-2.41,95%CI=(-6.88,2.05),P=0.29]。
FNS治疗股骨颈骨折可缩短骨折愈合时间;降低骨不连、股骨头坏死及内固定失败的发生率和半透明率;减少术中出血量和术后并发症;改善髋关节功能和活动能力。我们坚信FNS作为一种有效且安全的股骨颈骨折内固定方法,优于CCS这一研究结果。