大蒜（）和生姜（）粗提物对多重耐药性（MDR）家禽病原体的抗菌效果评估
Evaluation of antibacterial efficacy of garlic () and ginger () crude extract against multidrug-resistant (MDR) poultry pathogen.
作者信息
Noman Zakaria Al, Anika Tasnia Tabassum, Sachi Sabbya, Ferdous Jannatul, Sarker Yousuf Ali, Sabur Md Abdus, Rahman Md Tanvir, Sikder Mahmudul Hasan
机构信息
Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Department of Microbiology and Hygiene, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh.
出版信息
J Adv Vet Anim Res. 2023 Jun 30;10(2):151-156. doi: 10.5455/javar.2023.j664. eCollection 2023 Jun.
OBJECTIVE
The study is aimed to understand the antibacterial sensitivity of native and Indian varieties of garlic () and ginger () crude extracts against multidrug-resistant (MDR) poultry pathogen ( and sp.).
MATERIALS AND METHODS
Thin layer chromatography (TLC) is used to identify the target spices' bioactive antibacterial compounds. MDR and sp. were isolated from poultry. The TLC-Bioautography technique was applied to explore the antibacterial potentiality of garlic and ginger.
RESULTS
Inhibitory activities of garlic were Zone of inhibition (ZI) = 14.03 ± 0.15 mm and 19.70 ± 0.36 mm, Minimum inhibitory concentration (MIC): 0.625 and 0.325 mg/ml, and ginger were ZI = 14.63 ± 0.30 mm and 11.56 ± 0.51mm, MIC: 9.0 mg/ml against sp., respectively. Two bands of garlic ( value = 0.31 and 0.50) and one band of ginger ( value = 0.71) showed inhibitory potential in TLC-Bioautography against both MDR isolates.
CONCLUSION
Garlic and ginger were effective against MDR and sp These spices could be a suitable alternative during the antibiotic void.
目的
本研究旨在了解本地和印度品种大蒜（）和生姜（）粗提物对多重耐药（MDR）家禽病原体（和sp.）的抗菌敏感性。
材料与方法
采用薄层色谱（TLC）法鉴定目标香料的生物活性抗菌化合物。从家禽中分离出多重耐药和sp.。应用TLC-生物自显影技术探究大蒜和生姜的抗菌潜力。
结果
大蒜对sp.的抑菌活性为抑菌圈（ZI）=14.03±0.15毫米和19.70±0.36毫米，最低抑菌浓度（MIC）：0.625和0.325毫克/毫升；生姜对sp.的抑菌活性为ZI = 14.63±0.30毫米和11.56±0.51毫米，MIC：9.0毫克/毫升。在TLC-生物自显影中，大蒜的两条带（比移值=0.31和0.50）和生姜的一条带（比移值=0.71）对两种多重耐药分离株均显示出抑制潜力。
结论
大蒜和生姜对多重耐药和sp.有效。在抗生素空白期，这些香料可能是合适的替代品。
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