University of Pittsburgh Medical Center, Central Pennsylvania the United States (Drs Aljazeeri, Ramesh, and Rahman and Mss Wert and Klinger); Drexel University College of Medicine, Philadelphia, Pennsylvania, the United States (Drs Aljazeeri, Abdelhalim, and Ramesh); and Imam Abdulrahman Bin Faisal University, College of Medicine, Dammam, Saudi Arabia (Dr Almusally).
J Cardiopulm Rehabil Prev. 2023 Nov 1;43(6):438-443. doi: 10.1097/HCR.0000000000000813. Epub 2023 Aug 4.
Patients with COVID-19 often report persistent respiratory symptoms. Limited data exist on how to mitigate long-term sequelae of exercise intolerance and dyspnea. We aimed to study the role of pulmonary rehabilitation (PR) in patients with post-COVID-19.
This was an observational study. Consecutive patients with post-COVID-19, admitted to three separate outpatient PR programs, were enrolled. The program consisted of 8-12 wk of PR sessions (3 times/wk). Data were gathered at the initial visit and discharge. The primary outcome was the change in the 6-min walk test (6MWT) distance. Secondary outcomes included the Shortness of Breath Questionnaire (SOBQ), modified Borg dyspnea scale, Patient Health Questionnaire-9 (PHQ-9), and Lung Information Needs Questionnaire (LINQ).
A total of 56 patients completed the PR program (age 62.8 ± 14.7 yr, 57% were men). At baseline, the mean 6MWT was 313.3 ± 193.8 m. On average, the 6MWT improved by 84.3 m after PR ( P < .0001). Apart from the modified Borg dyspnea scale, there was improvement across secondary outcomes: SOBQ (-16.9 points), PHQ-9 (-2.6 points), and LINQ (-4.2 points); all P < .05.
Pulmonary rehabilitation showed a promising positive effect on patients with with post-COVID-19. It improved exercise capacity, perception of dyspnea, depressive symptoms, and patient knowledge needed to manage their lung disease. Pulmonary rehabilitation should be considered for post-COVID-19 patients.
患有 COVID-19 的患者常报告持续性呼吸道症状。关于如何减轻运动不耐受和呼吸困难的长期后遗症,目前的数据有限。我们旨在研究肺康复(PR)在 COVID-19 后的作用。
这是一项观察性研究。连续入组了 3 个单独的门诊 PR 项目中患有 COVID-19 后的患者。该方案包括 8-12 周的 PR 疗程(每周 3 次)。数据在初次就诊和出院时收集。主要结局是 6 分钟步行试验(6MWT)距离的变化。次要结局包括呼吸困难问卷(SOBQ)、改良 Borg 呼吸困难量表、患者健康问卷-9(PHQ-9)和肺信息需求问卷(LINQ)。
共有 56 名患者完成了 PR 方案(年龄 62.8±14.7 岁,57%为男性)。基线时,6MWT 的平均距离为 313.3±193.8 m。PR 后,6MWT 平均提高了 84.3 m(P<0.0001)。除了改良 Borg 呼吸困难量表外,其他次要结局均有改善:SOBQ(-16.9 分)、PHQ-9(-2.6 分)和 LINQ(-4.2 分);所有 P<0.05。
肺康复对 COVID-19 后患者显示出有希望的积极效果。它提高了运动能力、呼吸困难的感知、抑郁症状以及管理肺部疾病所需的患者知识。肺康复应考虑用于 COVID-19 后患者。