Yu Yan, Liao Yu, Zhang Shuting, Wei Lingling, Mi Na, Li Wenjing
Altern Ther Health Med. 2023 Oct;29(7):404-411.
Pancreatic cancer (PC) is one of the most malignant digestive cancers, characterized by a poor prognosis. PC patients receiving chemotherapy can endure immense physical and psychological pain, negatively impacting spiritual well-being and QoL.
The study intended to investigate PC patients' statuses regarding spiritual well-being and QoL, to identify and analyze the influencing factors, and to develop feasible spiritual-care plans, which could provide a reference for clinicians in promoting the spiritual well-being and QoL of PC chemotherapy patients.
The research team performed a prospective survey.
The study took place at the Second Affiliated Hospital of the Army Medical University in Chongqing, China.
Participants were 120 patients who underwent chemotherapy for pancreatic cancer (PC) at the hospital between November 2020 and April 2022. The research team selected participants using convenience sampling.
The outcome measures included: (1) a self-designed questionnaire to identify participants' demographic and clinical characteristics and (2) the Functional Assessment of Chronic Illness Therapy-Spiritual Well-being Scales (FACIT-Sp). The research team used the FACIT-Sp's two subscales, FACT-G and the FACIT-Sp-12, to evaluate participants' quality of life (QoL) and spiritual well-being, respectively.
The total scores for participants' spiritual well-being and QoL were 26.2 ± 5.39 and 65.44 ± 17.1, respectively. Spiritual well-being was positively correlated with the QoL (P < .001). According to the multiple linear regression analysis, the main factors influencing spiritual well-being were age (P < .01), education level (P < .001), average monthly income per capita of the family (P < .001), recurrence (P < .001), and pain (P < .05). The main factors influencing QoL were age (P = .008), education level (P < .001), average monthly income per capita of the family (P < .001), recurrence (P < .001), and pain (P < .01).
Patients who undergo chemotherapy for PC experience a low-to-medium level of spiritual well-being and a medium level of QoL. The detrimental factors include: (1) being middle-aged, (2) having a low education level, (3) having a low family income, (4) suffering a recurrence of the disease, and (5) experiencing moderate-to-severe pain. Medical practitioners should provide extra care and support to protect the spiritual well-being of these patients and ultimately improve their QoL.
胰腺癌（PC）是最具恶性的消化系统癌症之一，预后较差。接受化疗的PC患者会承受巨大的身心痛苦，对精神健康和生活质量产生负面影响。
本研究旨在调查PC患者的精神健康和生活质量状况，识别并分析影响因素，制定可行的精神关怀计划，为临床医生促进PC化疗患者的精神健康和生活质量提供参考。
研究团队进行了一项前瞻性调查。
研究在中国重庆陆军军医大学第二附属医院进行。
参与者为2020年11月至2022年4月期间在该医院接受胰腺癌化疗的120名患者。研究团队采用便利抽样法选择参与者。
结果指标包括：（1）一份自行设计的问卷，用于确定参与者的人口统计学和临床特征；（2）慢性病治疗功能评估-精神健康量表（FACIT-Sp）。研究团队分别使用FACIT-Sp的两个子量表FACT-G和FACIT-Sp-12来评估参与者的生活质量（QoL）和精神健康状况。
参与者的精神健康和生活质量总分分别为26.2±5.39和65.44±17.1。精神健康与生活质量呈正相关（P<.001）。根据多元线性回归分析，影响精神健康的主要因素为年龄（P<.01）、教育水平（P<.001）、家庭人均月收入（P<.001）、复发情况（P<.001）和疼痛程度（P<.05）。影响生活质量的主要因素为年龄（P=.008）、教育水平（P<.001）、家庭人均月收入（P<.001）、复发情况（P<.001）和疼痛程度（P<.01）。
接受PC化疗的患者精神健康水平为中低等，生活质量为中等水平。不利因素包括：（1）中年；（2）教育水平低；（3）家庭收入低；（4）疾病复发；（5）经历中度至重度疼痛。医生应提供额外的关怀和支持，以保护这些患者的精神健康，最终提高他们的生活质量。
