Division of Neonatology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Division of Neonatology, Department of Pediatrics, Children's Healthcare of Atlanta and Emory University School of Medicine, 2015 Uppergate Drive Northeast, Atlanta, GA 30322, USA.
Clin Perinatol. 2023 Sep;50(3):643-652. doi: 10.1016/j.clp.2023.04.006. Epub 2023 May 26.
Multicomponent fortification is the standard of care to support short-term growth in preterm infants receiving human milk. There is no consensus regarding the optimal timing, method, or products used to fortify human milk. Both bovine milk-based and human milk-based human milk fortifiers are safe options, though increased fortification and enrichment may be needed to achieve adequate growth. Additional studies are needed to evaluate newer fortifier products and fortification strategies.
多种成分强化是支持接受母乳的早产儿短期生长的标准护理。对于最佳强化时机、方法或产品尚未达成共识。牛乳制品和人乳来源的人乳强化剂均为安全选择,但可能需要增加强化和增稠以实现充足的生长。需要进一步研究来评估新的强化剂产品和强化策略。