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本文引用的文献

1
Transfer-RNA, an early gene?转运核糖核酸,一种早期基因?
Naturwissenschaften. 1981 Jun;68(6):282-92. doi: 10.1007/BF01047470.
2
Periodic correlations in DNA sequences and evidence suggesting their evolutionary origin in a comma-less genetic code.DNA序列中的周期性相关性以及表明其在无逗号遗传密码中进化起源的证据。
J Mol Evol. 1981;17(2):94-102. doi: 10.1007/BF01732679.
3
Codon catalog usage is a genome strategy modulated for gene expressivity.密码子编目使用是一种为基因表达性而调节的基因组策略。
Nucleic Acids Res. 1981 Jan 10;9(1):r43-74. doi: 10.1093/nar/9.1.213-b.
4
Thermodynamic approach to a possible theory of the evolution of a genetic code.遗传密码进化可能理论的热力学方法。
Z Naturforsch C Biosci. 1982 Oct;37(10):1031-7. doi: 10.1515/znc-1982-1025.
5
Recognition of protein coding regions in DNA sequences.DNA序列中蛋白质编码区域的识别。
Nucleic Acids Res. 1982 Sep 11;10(17):5303-18. doi: 10.1093/nar/10.17.5303.
6
Nucleotide sequences from the adenovirus-2 genome.来自腺病毒2型基因组的核苷酸序列。
J Biol Chem. 1982 Nov 25;257(22):13475-91.
7
Codon preference and its use in identifying protein coding regions in long DNA sequences.密码子偏好性及其在长DNA序列中识别蛋白质编码区的应用。
Nucleic Acids Res. 1982 Jan 11;10(1):141-56. doi: 10.1093/nar/10.1.141.
8
Method to determine the reading frame of a protein from the purine/pyrimidine genome sequence and its possible evolutionary justification.从嘌呤/嘧啶基因组序列确定蛋白质阅读框的方法及其可能的进化依据。
Proc Natl Acad Sci U S A. 1981 Mar;78(3):1596-600. doi: 10.1073/pnas.78.3.1596.
9
Organization and expression of eucaryotic split genes coding for proteins.编码蛋白质的真核生物断裂基因的组织与表达。
Annu Rev Biochem. 1981;50:349-83. doi: 10.1146/annurev.bi.50.070181.002025.
10
Statistical evaluation of the coding capacity of complementary DNA strands.互补DNA链编码能力的统计学评估。
Nucleic Acids Res. 1984 Jun 25;12(12):5049-59. doi: 10.1093/nar/12.12.5049.

DNA序列编码的概率:一种根据热力学特征预测翻译阅读框的算法。

Probability of coding of a DNA sequence: an algorithm to predict translated reading frames from their thermodynamic characteristics.

作者信息

Tramontano A, Macchiato M F

出版信息

Nucleic Acids Res. 1986 Jan 10;14(1):127-35. doi: 10.1093/nar/14.1.127.

DOI:10.1093/nar/14.1.127
PMID:3753761
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC339361/
Abstract

An algorithm to determine the probability that a reading frame codifies for a protein is presented. It is based on the results of our previous studies on the thermodynamic characteristics of a translated reading frame. We also develop a prediction procedure to distinguish between coding and non-coding reading frames. The procedure is based on the characteristics of the putative product of the DNA sequence and not on periodicity characteristics of the sequence, so the prediction is not biased by the presence of overlapping translated reading frames or by the presence of translated reading frames on the complementary DNA strand.

摘要

本文提出了一种确定阅读框编码蛋白质概率的算法。该算法基于我们之前对翻译阅读框热力学特性的研究结果。我们还开发了一种预测程序,以区分编码阅读框和非编码阅读框。该程序基于DNA序列推定产物的特征,而非序列的周期性特征,因此预测不会因重叠翻译阅读框的存在或互补DNA链上翻译阅读框的存在而产生偏差。