DNA序列编码的概率：一种根据热力学特征预测翻译阅读框的算法。
Probability of coding of a DNA sequence: an algorithm to predict translated reading frames from their thermodynamic characteristics.
作者信息
Tramontano A, Macchiato M F
出版信息
Nucleic Acids Res. 1986 Jan 10;14(1):127-35. doi: 10.1093/nar/14.1.127.
Abstract
An algorithm to determine the probability that a reading frame codifies for a protein is presented. It is based on the results of our previous studies on the thermodynamic characteristics of a translated reading frame. We also develop a prediction procedure to distinguish between coding and non-coding reading frames. The procedure is based on the characteristics of the putative product of the DNA sequence and not on periodicity characteristics of the sequence, so the prediction is not biased by the presence of overlapping translated reading frames or by the presence of translated reading frames on the complementary DNA strand.
摘要
本文提出了一种确定阅读框编码蛋白质概率的算法。该算法基于我们之前对翻译阅读框热力学特性的研究结果。我们还开发了一种预测程序，以区分编码阅读框和非编码阅读框。该程序基于DNA序列推定产物的特征，而非序列的周期性特征，因此预测不会因重叠翻译阅读框的存在或互补DNA链上翻译阅读框的存在而产生偏差。
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Codon catalog usage is a genome strategy modulated for gene expressivity.密码子编目使用是一种为基因表达性而调节的基因组策略。
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