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密码子偏好性及其在长DNA序列中识别蛋白质编码区的应用。

Codon preference and its use in identifying protein coding regions in long DNA sequences.

作者信息

Staden R, McLachlan A D

出版信息

Nucleic Acids Res. 1982 Jan 11;10(1):141-56. doi: 10.1093/nar/10.1.141.

DOI:10.1093/nar/10.1.141
PMID:7063399
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC326122/
Abstract

This paper describes a computer method that uses codon preference to help find protein coding regions in long DNA sequences. The method can distinguish between introns and exons and can help to detect sequencing errors.

摘要

本文描述了一种计算机方法,该方法利用密码子偏好性来帮助在长DNA序列中寻找蛋白质编码区域。该方法能够区分内含子和外显子,并且有助于检测测序错误。

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Codon preference and its use in identifying protein coding regions in long DNA sequences.密码子偏好性及其在长DNA序列中识别蛋白质编码区的应用。
Nucleic Acids Res. 1982 Jan 11;10(1):141-56. doi: 10.1093/nar/10.1.141.
2
The codon preference plot: graphic analysis of protein coding sequences and prediction of gene expression.密码子偏好性图:蛋白质编码序列的图形分析及基因表达预测
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本文引用的文献

1
A computer program to search for tRNA genes.一个用于搜索转运RNA基因的计算机程序。
Nucleic Acids Res. 1980 Feb 25;8(4):817-25.
2
Some rules in the ordering of nucleotides in the DNA.DNA中核苷酸排列的一些规则。
Nucleic Acids Res. 1980 Oct 10;8(19):4545-62. doi: 10.1093/nar/8.19.4545.
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Preferential codon usage in genes.基因中的密码子偏好性使用
Gene. 1981 May;13(4):355-64. doi: 10.1016/0378-1119(81)90015-9.
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Sequence and organization of the human mitochondrial genome.人类线粒体基因组的序列与组织
Nature. 1981 Apr 9;290(5806):457-65. doi: 10.1038/290457a0.
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Codon catalog usage and the genome hypothesis.密码子目录使用与基因组假说。
Nucleic Acids Res. 1980 Jan 11;8(1):r49-r62. doi: 10.1093/nar/8.1.197-c.
6
Method to determine the reading frame of a protein from the purine/pyrimidine genome sequence and its possible evolutionary justification.从嘌呤/嘧啶基因组序列确定蛋白质阅读框的方法及其可能的进化依据。
Proc Natl Acad Sci U S A. 1981 Mar;78(3):1596-600. doi: 10.1073/pnas.78.3.1596.
7
The coding function of nucleotide sequences can be discerned by statistical analysis.核苷酸序列的编码功能可以通过统计分析来识别。
J Theor Biol. 1981 Feb 7;88(3):409-20. doi: 10.1016/0022-5193(81)90274-5.
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The atp operon: nucleotide sequence of the promoter and the genes for the membrane proteins, and the delta subunit of Escherichia coli ATP-synthase.ATP操纵子:大肠杆菌ATP合酶膜蛋白及δ亚基基因启动子的核苷酸序列
Nucleic Acids Res. 1981 Aug 25;9(16):3919-26. doi: 10.1093/nar/9.16.3919.
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Molecular analysis of the unc-54 myosin heavy-chain gene of Caenorhabditis elegans.秀丽隐杆线虫unc-54肌球蛋白重链基因的分子分析。
Nature. 1981 Jun 4;291(5814):386-90. doi: 10.1038/291386a0.
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Nucleotide sequence of bacteriophage fd DNA.噬菌体fd DNA的核苷酸序列。
Nucleic Acids Res. 1978 Dec;5(12):4495-503. doi: 10.1093/nar/5.12.4495.