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Pruritus as an early sign of abnormal scarring in the re-epithelialising phase of Toxic Epidermal Necrolysis.

作者信息

Frederiks Aaron J, Korbl Jasmin D, Ardakani Nima Mesbah, Wood Fiona M, Ricciardo Bernadette

机构信息

Department of Dermatology Fiona Stanley Hospital Murdoch Western Australia Australia.

Faculty of Health and Medical Sciences School of Medicine The University of Western Australia Perth Western Australia Australia.

出版信息

Skin Health Dis. 2023 Feb 15;3(4):e217. doi: 10.1002/ski2.217. eCollection 2023 Aug.

DOI:10.1002/ski2.217
PMID:37538333
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10395619/
Abstract

We present a 28-year-old remote-living male who presented to our dermatology clinic with increasing pruritus over his torso and limbs in the context of a recent admission for Toxic Epidermal Necrolysis (TEN) secondary to paliperidone depot. Our case demonstrates that pruritus in the re-epithelialising phase of TEN may be a sign of abnormal scarring. Early assessment and measurement for compression garments is recommended.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df32/10395619/757e7f358271/SKI2-3-e217-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df32/10395619/b1f10d81cc70/SKI2-3-e217-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df32/10395619/757e7f358271/SKI2-3-e217-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df32/10395619/b1f10d81cc70/SKI2-3-e217-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df32/10395619/757e7f358271/SKI2-3-e217-g001.jpg

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本文引用的文献

1
Long-term complications of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN): the spectrum of chronic problems in patients who survive an episode of SJS/TEN necessitates multidisciplinary follow-up.史蒂文斯-约翰逊综合征/中毒性表皮坏死松解症（SJS/TEN）的长期并发症：存活 SJS/TEN 发作的患者存在一系列慢性问题，需要多学科随访。
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2
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Wound Repair Regen. 2015 Jul-Aug;23(4):531-7. doi: 10.1111/wrr.12302. Epub 2015 Jun 24.
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Extensive hypertrophic scarring after toxic epidermal necrolysis in a child.
Pediatr Dermatol. 2014 Jul-Aug;31(4):527-8. doi: 10.1111/j.1525-1470.2012.01863.x. Epub 2012 Oct 2.
4
Delayed reepithelialization and scarring deregulation following drug-induced toxic epidermal necrolysis.
Burns. 2007 Feb;33(1):100-4. doi: 10.1016/j.burns.2006.04.031. Epub 2006 Oct 31.
5
Silicone gel treatment of extensive hypertrophic scarring following toxic epidermal necrolysis.
Br J Dermatol. 1994 Apr;130(4):540-1. doi: 10.1111/j.1365-2133.1994.tb03396.x.