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尿路感染患者的大肠杆菌脑膜炎:一例报告

Escherichia coli Meningitis in a Patient With Urinary Tract Infection: A Case Report.

作者信息

Memia Aglisa, Deda Xheni, Broka Andrea, Kawalet Mariana, Berger Judith

机构信息

Medicine, St. Barnabas Hospital (SBH) Health System, Bronx, USA.

Hepatology, Missouri University Hospital, Columbia, USA.

出版信息

Cureus. 2023 Jul 3;15(7):e41312. doi: 10.7759/cureus.41312. eCollection 2023 Jul.

Abstract

This article discusses a case of (E. coli) meningitis resulting in altered mental status in a patient with multiple pre-existing comorbidities. The case highlights the underestimated risk of community-acquired gram-negative meningitis in adults, which can have a high mortality rate, particularly in elderly patients with sepsis and urinary tract infections. Diagnosis of meningitis was confirmed by analyzing cerebrospinal fluid obtained through the lumbar puncture and blood cultures. Treatment involved prompt administration of antibiotics and supportive care. However, the emergence of antibiotic resistance, such as extended-spectrum beta-lactamase production, in community-acquired meningitis is an increasing concern. Therefore, early recognition and appropriate management are crucial in the diagnosis and treatment of this life-threatening condition.

摘要

本文讨论了一例大肠杆菌性脑膜炎导致一名患有多种并存疾病的患者精神状态改变的病例。该病例凸显了成人社区获得性革兰氏阴性菌脑膜炎被低估的风险,这种脑膜炎死亡率可能很高,尤其是在患有败血症和尿路感染的老年患者中。通过分析经腰椎穿刺获取的脑脊液和血培养确诊了大肠杆菌性脑膜炎。治疗包括及时使用抗生素和支持性护理。然而,社区获得性大肠杆菌性脑膜炎中抗生素耐药性的出现,如超广谱β-内酰胺酶的产生,日益受到关注。因此,早期识别和恰当处理对于诊断和治疗这种危及生命的疾病至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ea2/10395550/b837376c74b5/cureus-0015-00000041312-i01.jpg

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