一个使用多个标记位点计算X连锁疾病风险的计算机程序。
A computer programme to calculate risk in X linked disorders using multiple marker loci.
作者信息
Clayton J F
出版信息
J Med Genet. 1986 Feb;23(1):35-9. doi: 10.1136/jmg.23.1.35.
Abstract
A computer programme package has been written which calculates the genetic risk (recurrence risk) for X linked disorders, incorporating data from multiple probes. The programme can allow new mutation and the incorporation of other predictors of the disease genotype of the subjects in the family.
摘要
已经编写了一个计算机程序包，该程序包结合来自多个探针的数据，计算X连锁疾病的遗传风险（复发风险）。该程序可以考虑新的突变，并纳入家族中受试者疾病基因型的其他预测因素。
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Duchenne muscular dystrophy. Genetic aspects, carrier detection and antenatal diagnosis.杜氏肌营养不良症。遗传学方面、携带者检测及产前诊断。
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Linkage relationship of a cloned DNA sequence on the short arm of the X chromosome to Duchenne muscular dystrophy.X染色体短臂上一个克隆DNA序列与杜氏肌营养不良症的连锁关系。
Nature. 1982 Nov 4;300(5887):69-71. doi: 10.1038/300069a0.
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Genetic linkage between Becker muscular dystrophy and a polymorphic DNA sequence on the short arm of the X chromosome.贝克肌肉萎缩症与X染色体短臂上一个多态性DNA序列之间的基因连锁。
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Close genetic linkage between X-linked retinitis pigmentosa and a restriction fragment length polymorphism identified by recombinant DNA probe L1.28.X连锁视网膜色素变性与经重组DNA探针L1.28鉴定的限制性片段长度多态性之间的紧密遗传连锁。
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