利用侧翼标记基因座估计单基因疾病的复发风险。
The estimation of recurrence risks in monogenic disorders using flanking marker loci.
作者信息
Winter R M
出版信息
J Med Genet. 1985 Feb;22(1):12-5. doi: 10.1136/jmg.22.1.12.
Abstract
A method is presented of calculating recurrence risks at a disease locus where there is information from flanking marker loci. This method uses output from the computer programme LIPED. Information from carrier detection tests and mutation at the disease locus can be taken into account in certain pedigrees.
摘要
本文提出了一种在存在侧翼标记基因座信息的疾病基因座处计算复发风险的方法。该方法使用计算机程序LIPED的输出结果。在某些家系中，可以考虑携带者检测试验的信息以及疾病基因座处的突变情况。
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引用本文的文献
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本文引用的文献
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Am J Hum Genet. 1984 Mar;36(2):460-5.
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A computer program for linkage analysis of general human pedigrees.一种用于普通人类家系连锁分析的计算机程序。
Am J Hum Genet. 1976 Sep;28(5):528-9.
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