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[与急性休止期脱发相关的新冠后综合征综述]

[Review of the post-COVID-19 syndrome associated to acute telogen effluvium].

作者信息

Chávez-Chavira Grecia

机构信息

Universidad Autónoma de Chihuahua, Facultad de Medicina y Ciencias Biomédicas, División de Investigación y Posgrado. Chihuahua, Chihuahua, México.

出版信息

Rev Med Inst Mex Seguro Soc. 2023 Jul 31;61(4):496-501. doi: 10.5281/zenodo.8200471.

DOI:10.5281/zenodo.8200471
PMID:37540705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10521875/
Abstract

Coronavirus disease 2019 (COVID-19) has impacted our society in numerous ways. So far (November 2022) around 640 million SARS-CoV-2 infections have been confirmed worldwide. It is known that this disease has a main affection at the cardiopulmonary level, however, it affects almost all the organs and systems of the body, including the skin. Post-COVID-19 syndrome occurs in some patients, leaving significant sequelae that impact their quality of life. Among the most common sequelae are: cough, dyspnea, chronic fatigue, hyposmia and dysosmia. In addition to these, other sequelae not related to respiratory syndrome have been reported, such as hair loss, which has been observed in around 20% of post-COVID-19 patients, this could be attributable to acute telogen effluvium (TE). To date, no study has been conducted to determine the relationship of ET in those who have had COVID-19. Acute ET is defined as diffuse, non-scarring hair loss, usually self-limited, lasting for about 6 months. Within its etiology, severe systemic febrile illness, pregnancy, restrictive diets, severe stress and various drugs have been described. It seriously affects the quality of life of patients and is often associated with loss of confidence and low self-esteem.

摘要

2019冠状病毒病(COVID-19)在许多方面对我们的社会产生了影响。截至2022年11月,全球已确诊约6.4亿例严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染病例。众所周知,这种疾病主要影响心肺系统,然而,它几乎会影响身体的所有器官和系统,包括皮肤。一些COVID-19患者会出现新冠后综合征,留下严重的后遗症,影响他们的生活质量。最常见的后遗症包括:咳嗽、呼吸困难、慢性疲劳、嗅觉减退和嗅觉障碍。除此之外,还报告了其他与呼吸综合征无关的后遗症,如脱发,在约20%的COVID-19康复患者中观察到了这种情况,这可能归因于急性休止期脱发(TE)。迄今为止,尚未进行研究来确定休止期脱发在感染过COVID-19的人群中的情况。急性休止期脱发被定义为弥漫性、非瘢痕性脱发,通常具有自限性,持续约6个月。在其病因中,已描述了严重的全身性发热性疾病、妊娠、限制性饮食、严重应激和各种药物。它严重影响患者的生活质量,并且常常与信心丧失和自卑相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e7d/10521875/fd16d2d58dc7/04435117-61-4-496-c001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e7d/10521875/fd16d2d58dc7/04435117-61-4-496-c001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e7d/10521875/fd16d2d58dc7/04435117-61-4-496-c001.jpg

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本文引用的文献

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COVID-19 infection is a major cause of acute telogen effluvium.COVID-19 感染是急性休止期脱发的主要原因。
Ir J Med Sci. 2022 Aug;191(4):1677-1681. doi: 10.1007/s11845-021-02754-5. Epub 2021 Aug 31.
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Trichodynia and telogen effluvium in COVID-19 patients: Results of an international expert opinion survey on diagnosis and management.新冠病毒感染患者的拔毛癖和休止期脱发:一项关于诊断和管理的国际专家意见调查结果
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Pathobiology questions raised by telogen effluvium and trichodynia in COVID-19 patients.新冠病毒感染患者休止期脱发和毛发疼痛引发的病理生物学问题
Exp Dermatol. 2021 Jul;30(7):999-1000. doi: 10.1111/exd.14352. Epub 2021 May 4.
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Post-acute COVID-19 syndrome.新冠病毒感染后长期综合征。
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Managing the long term effects of covid-19: summary of NICE, SIGN, and RCGP rapid guideline.应对新冠病毒病的长期影响:英国国家卫生与临床优化研究所、苏格兰校际指南网络和皇家全科医师学院快速指南总结
BMJ. 2021 Jan 22;372:n136. doi: 10.1136/bmj.n136.
10
Telogen effluvium associated with COVID-19 infection.与 COVID-19 感染相关的休止期脱发。
Dermatol Ther. 2021 Mar;34(2):e14761. doi: 10.1111/dth.14761. Epub 2021 Jan 14.