Wayne State University School of Medicine, Detroit, Michigan, USA.
Department of Dermatology, Henry Ford Hospital, Detroit, Michigan, USA.
Dermatol Ther. 2021 Mar;34(2):e14761. doi: 10.1111/dth.14761. Epub 2021 Jan 14.
Telogen effluvium (TE) is characterized by diffuse hair shedding 2-3 months after a stressor, and COVID-19 infection is potentially one such stressor. Those who were infected with the virus were under immense psychosocial and physiologic stress. We retrospectively reviewed electronic medical records of 552 patients who were evaluated by a Henry Ford Health System dermatologist between February 2020 and September 2020 and had a diagnosis of COVID-19 infection. Ten patients were identified with TE attributed to COVID-19 infection and described their presentations as a case series. For the ten patients selected, the mean age was 48.5 years old and 90% were female. Six of the patients were Black, one Middle Eastern, and three White. On average, the hair shedding began 50 days after the first symptom of COVID-19 infection. About 80% of these patients were treated with antibiotics, systemic corticosteroids, and/or hydroxychloroquine for their COVID-19 infection and 70% were hospitalized. The presentations of these patients suggest that COVID-19 infection may be a significant trigger of TE. TE caused by hydroxychloroquine, azithromycin or other medications cannot be ruled out, and the global pandemic itself is a source of psychosocial stress. Further studies will be needed to understand the long-term prevalence and prognosis of TE associated with COVID-19 infection.
休止期脱发(TE)的特征是在应激源后 2-3 个月出现弥漫性脱发,而 COVID-19 感染可能就是这样的应激源之一。那些感染病毒的人承受着巨大的心理社会和生理压力。我们回顾性地审查了 2020 年 2 月至 2020 年 9 月期间在亨利福特健康系统皮肤科医生处就诊并被诊断为 COVID-19 感染的 552 名患者的电子病历。有 10 名患者被确定为 COVID-19 感染引起的 TE,并将其表现描述为病例系列。在选择的 10 名患者中,平均年龄为 48.5 岁,90%为女性。6 名患者为黑人,1 名患者为中东人,3 名患者为白人。平均而言,脱发开始于 COVID-19 感染的第一个症状后 50 天。这些患者中约有 80%因 COVID-19 感染接受了抗生素、全身皮质类固醇和/或羟氯喹治疗,70%住院。这些患者的表现表明 COVID-19 感染可能是 TE 的一个重要诱因。不能排除由羟氯喹、阿奇霉素或其他药物引起的 TE,全球大流行本身就是心理压力的一个来源。需要进一步的研究来了解与 COVID-19 感染相关的 TE 的长期患病率和预后。