Manet Romain, Czosnyka Zofia, Czosnyka Marek, Gergelé Laurent, Jouanneau Emmanuel, Garnier-Crussard Antoine, Desestret Virginie, Palandri Giorgio
Department of Neurosurgery B, Neurological Hospital P. Wertheimer, University of Lyon, France.
Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital, University of Cambridge, UK.
World Neurosurg. 2023 Oct;178:e6-e12. doi: 10.1016/j.wneu.2023.07.147. Epub 2023 Aug 4.
Idiopathic normal pressure hydrocephalus (iNPH) refers to a complex brain disorder characterized by ventricular enlargement and the classic Hakim's triad of gait and balance difficulties, urinary incontinence, and cognitive impairment. It predominantly affects older patients in the absence of an identified cause. As the elderly population continues to increase, iNPH becomes a growing concern in the complex spectrum of neuro-geriatric care, with significant socio-economic implications. However, unlike other well-structured management approaches for neurodegenerative disorders, the management of iNPH remains largely uncodified, leading to suboptimal care in many cases. In this article, we highlighted the challenges of current practice and identify key points for an optimal structuration of care for iNPH. Adopting a global approach to iNPH could facilitate a progressive shift in mindset, moving away from solely aiming to cure an isolated neurological disease with uncertain outcomes to providing comprehensive care that focuses on improving the daily life of frail patients with complex neurodegenerative burdens, using tailored goals.
特发性正常压力脑积水(iNPH)是一种复杂的脑部疾病,其特征为脑室扩大以及典型的哈基姆三联征,即步态和平衡障碍、尿失禁及认知障碍。该病主要影响老年患者,且病因不明。随着老年人口持续增加,iNPH在复杂的神经老年护理领域日益受到关注,具有重大的社会经济影响。然而,与其他针对神经退行性疾病的结构化管理方法不同,iNPH的管理在很大程度上仍未规范化,导致许多情况下治疗效果欠佳。在本文中,我们强调了当前实践面临的挑战,并确定了iNPH最佳护理结构化的关键点。采用全球视角看待iNPH有助于实现思维方式的逐步转变,从单纯致力于治疗一种预后不确定的孤立神经系统疾病,转向提供全面护理,即通过设定个性化目标,关注改善患有复杂神经退行性负担的体弱患者的日常生活。