Department of Respiratory Diseases and Allergy in Children, SI "Institute of Pediatrics, Obstetrics and Gynecology named after Academician O.M. Lukyanova, National Academy of Medical Sciences of Ukraine", Kyiv, Ukraine.
Department of Pediatrics, CNE "Kyiv City Children's Clinical Infectious Disease Hospital", Kyiv, Ukraine.
J Mother Child. 2023 Aug 7;27(1):33-41. doi: 10.34763/jmotherandchild.20232701.d-23-00012. eCollection 2023 Jun 1.
In December 2019, the Chinese city of Wuhan reported the first cases of pneumonia from a new type of beta coronavirus named SARS-CoV-2. In the early days of the COVID-19 outbreak, paediatric patients were thought to be immune to the new virus; however, further studies have shown people of all ages to be susceptible to the virus.
Identify and describe the clinical and epidemiological features of COVID-19 among hospitalized children in Ukraine.
Retrospective study of 171 children aged 2 months to 18 years who were hospitalized with laboratory-confirmed SARS-CoV-2.
Most patients in the study had a moderate progression of the disease (77.78%, or n=133), whereas a severe course was noted in 22.22% (n=38). Across age groups, children aged 6-12 was the predominant age group affected (35.67%, or n=61). The most common symptoms were fever in 88.2% of patients, sore throat in 69.2% and cough in 60.9%. Symptoms associated with dyspnoea and cyanosis were significantly more common in children with the severe course (p<0.05). Almost half of children had at least one comorbidity, the most prevalent being chronic tonsillitis (11.8% of patients) and anemia (6.5% of patients). A positive correlation (r=0.7 p<0.05) was found between CRP levels and COVID-19 severity. X-ray changes in the lungs were present in 76.61% of examined children and ground-glass opacity symptom was registered in 50.88%.
COVID-19 among hospitalized children in Ukraine usually has a moderate course of illness and a good prognosis.
2019 年 12 月，中国武汉市报告了首例新型冠状病毒引起的肺炎病例，该病毒被命名为 SARS-CoV-2。在 COVID-19 疫情早期，人们认为儿科患者对这种新型病毒具有免疫力；然而，进一步的研究表明，所有年龄段的人都容易感染该病毒。
确定并描述乌克兰住院儿童 COVID-19 的临床和流行病学特征。
回顾性分析了 171 例年龄在 2 个月至 18 岁之间、经实验室确诊为 SARS-CoV-2 感染的住院患儿。
研究中大多数患者疾病进展为中度（77.78%，n=133），22.22%（n=38）为严重病例。各年龄组中，6-12 岁患儿为主要发病人群（35.67%，n=61）。最常见的症状是发热（88.2%的患者）、咽痛（69.2%）和咳嗽（60.9%）。有呼吸困难和发绀症状的患者在严重病例中更为常见（p<0.05）。几乎一半的患儿至少有一种合并症，最常见的是慢性扁桃体炎（11.8%的患者）和贫血（6.5%的患者）。CRP 水平与 COVID-19 严重程度呈正相关（r=0.7，p<0.05）。76.61%的检查患儿肺部 X 线有变化，50.88%的患儿出现磨玻璃影。
乌克兰住院儿童 COVID-19 通常呈中度疾病过程，预后良好。
