Fu Wayne, Adzhiashvili Victoria, Majlesi Nima
Emergency Medicine, Mercy Hospital, Buffalo, USA.
Emergency Medicine, Staten Island University Hospital, Staten Island, USA.
Cureus. 2023 Jul 6;15(7):e41464. doi: 10.7759/cureus.41464. eCollection 2023 Jul.
Background and objective The opioid use disorder (OUD) epidemic is a persistent public health crisis in the United States. Medication-assisted treatment (MAT) with opioid agonists, including buprenorphine, is an effective treatment and is commonly initiated in the emergency department (ED). This study describes the demographics and clinical characteristics of OUD patients presenting to the ED and evaluated for MAT. Methodology A retrospective, single-center descriptive study of 129 adult patients presenting to the ED between July 2018 and July 2020 with OUD and evaluated for MAT. Results A total of 129 patients were assessed for MAT. About half (53%) received MAT; the remaining received only a referral (35%) or declined any intervention (12%). The median age was 36 years interquartile range (IQR, 28-46 years) and predominantly male (73%), single (65%), white (73%), unemployed (57%) with public insurance (55%), and without a primary care physician (58%). Majority of the patients presented with opioid withdrawal (62%) or intoxication (15%), while 23% presented with other complaints. About half of the patients (51%) were discharged with a naloxone kit. The majority of the patients were induced with buprenorphine with 4 mg or less (54%) and only 6% of patients received repeat dosing. Conclusions Male, white patients who are unmarried and unemployed, lack primary care follow-up, and rely on public insurance are more likely to be candidates for MAT. Providers should always maintain a high suspicion of opioid misuse and optimize treatment for those in withdrawal. Understanding these characteristics in conjunction with recent health policy changes will hopefully guide and encourage ED-initiated interventions in combating the opioid crisis.
背景与目的 阿片类物质使用障碍(OUD)流行是美国持续存在的公共卫生危机。使用包括丁丙诺啡在内的阿片类激动剂进行药物辅助治疗(MAT)是一种有效的治疗方法,且通常在急诊科(ED)启动。本研究描述了到急诊科就诊并接受MAT评估的OUD患者的人口统计学和临床特征。方法 对2018年7月至2020年7月期间到急诊科就诊且患有OUD并接受MAT评估的129例成年患者进行回顾性单中心描述性研究。结果 共有129例患者接受了MAT评估。约一半(53%)接受了MAT;其余患者仅接受了转诊(35%)或拒绝任何干预(12%)。年龄中位数为36岁,四分位间距(IQR,28 - 46岁),主要为男性(73%)、单身(65%)、白人(73%)、失业(57%)、有公共保险(55%)且没有初级保健医生(58%)。大多数患者表现为阿片类物质戒断(62%)或中毒(15%),而23%表现为其他症状。约一半患者(51%)出院时配备了纳洛酮试剂盒。大多数患者使用4毫克或更低剂量的丁丙诺啡进行诱导(54%),只有6%的患者接受重复给药。结论 未婚、失业、缺乏初级保健随访且依赖公共保险的男性白人患者更有可能成为MAT的候选对象。医疗服务提供者应始终高度怀疑阿片类物质滥用,并优化对戒断患者的治疗。结合近期卫生政策变化了解这些特征有望指导并鼓励急诊科发起的应对阿片类危机的干预措施。