Branch OraLee H, Rikhy Mohit, Auster-Gussman Lisa A, Lockwood Kimberly G, Graham Sarah A
Lark Health Mountain View California USA.
Obes Sci Pract. 2023 Mar 7;9(4):404-415. doi: 10.1002/osp4.665. eCollection 2023 Aug.
Participation in the National Diabetes Prevention Program (DPP) can improve individual health through reduced risk of type 2 diabetes and save the healthcare system substantial medical costs associated with a diagnosis of type 2 diabetes and its associated complications. There is less evidence of outcomes and cost savings associated with a fully digital delivery of the DPP.
This study assessed 13,593 members who provided an initial digital weight and subsequently achieved various weight loss and engagement outcomes during their participation in a digital DPP. Analyzed data included both complete observations and missing observations imputed using maximum likelihood estimation. Findings include members' behavioral correlates of weight loss and a literature-based cost-savings estimate associated with achieving three mutually exclusive weight loss or engagement benchmarks: ≥5% weight loss, >2% but <5% weight loss, and completion of ≥4 educational lessons.
11,976 members (88%) provided a weight after 2 months of participation, enabling calculation of their weight nadir. Considering complete data, 97% of members maintained or lost weight. Using the imputed data for these calculations, 32.0% of members achieved ≥5%, 32.4% achieved >2% but <5%, 32.0% maintained ±2%, and 3.6% gained weight. Members who lost the most weight achieved their weight nadir furthest into the program (mean day = 189, SE = 1.4) and had the longest active engagement (mean days = 268, SE = 1.4), particularly compared to members who gained weight (mean nadir day = 119, SE = 3.7; active engagement mean days = 199, SE = 4.9) (both ≤ 0.0001). Modeled 1-year cost-savings estimates ranged from $11,229,160 to $12,960,875.
Members of a fully digital DPP achieved clinical and engagement outcomes during their participation in the program that confer important health benefits and cost savings.
参与国家糖尿病预防计划(DPP)可通过降低2型糖尿病风险改善个人健康状况,并为医疗保健系统节省与2型糖尿病诊断及其相关并发症相关的大量医疗费用。关于DPP完全数字化交付的结果和成本节约的证据较少。
本研究评估了13593名成员,他们提供了初始数字体重,并在参与数字DPP期间实现了各种体重减轻和参与结果。分析的数据包括完整观察值和使用最大似然估计法估算的缺失观察值。研究结果包括成员体重减轻的行为相关性,以及与实现三个相互排斥的体重减轻或参与基准相关的基于文献的成本节约估计:体重减轻≥5%、体重减轻>2%但<5%,以及完成≥4节教育课程。
11976名成员(88%)在参与2个月后提供了体重,从而能够计算出他们的最低体重。考虑完整数据,97%的成员体重维持不变或减轻。使用估算数据进行这些计算时,32.0%的成员体重减轻≥5%,32.4%的成员体重减轻>2%但<5%,32.0%的成员体重维持在±2%以内,3.6%的成员体重增加。体重减轻最多的成员在项目进行到最久时达到最低体重(平均天数=189,标准误=1.4),并且积极参与时间最长(平均天数=268,标准误=1.4),尤其是与体重增加的成员相比(最低体重平均天数=119,标准误=3.7;积极参与平均天数=199,标准误=4.9)(两者均≤0.0001)。模拟的1年成本节约估计在11229160美元至12960875美元之间。
完全数字化DPP的成员在参与项目期间取得了临床和参与成果,带来了重要的健康益处和成本节约。