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通过脑室内注射神经肽Y刺激饱足猪的进食。

Stimulation of feeding in the satiated pig by intracerebroventricular injection of neuropeptide Y.

作者信息

Parrott R F, Heavens R P, Baldwin B A

出版信息

Physiol Behav. 1986;36(3):523-5. doi: 10.1016/0031-9384(86)90325-2.

DOI:10.1016/0031-9384(86)90325-2
PMID:3754639
Abstract

Operant feeding and drinking were studied in satiated pigs following injection of 0 (saline vehicle control), 25, 50 or 100 micrograms neuropeptide Y into the lateral cerebral ventricles. Neuropeptide Y stimulated feeding in a dose related manner without any apparent aversive effects. No facilitation of drinking was observed.

摘要

在饱足的猪中，向其侧脑室注射0（生理盐水载体对照）、25、50或100微克神经肽Y后，对其操作性进食和饮水进行了研究。神经肽Y以剂量相关的方式刺激进食，且无明显厌恶效应。未观察到饮水增加。

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Stimulation of feeding in the satiated pig by intracerebroventricular injection of neuropeptide Y.通过脑室内注射神经肽Y刺激饱足猪的进食。
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Knockdown of neuropeptide Y in the dorsomedial hypothalamus reverses high-fat diet-induced obesity and impaired glucose tolerance in rats.
敲除大鼠下丘脑背内侧核中的神经肽Y可逆转高脂饮食诱导的肥胖及葡萄糖耐量受损。
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