Muntyanu Anastasiya, Ghazawi Feras M, Pastukhova Elena, Zubarev Andrei, Litvinov Ivan V
Division of Dermatology, McGill University, Montreal, QC, Canada.
Division of Dermatology, University of Ottawa, Ottawa, ON, Canada.
Front Med (Lausanne). 2023 Jul 20;10:1188038. doi: 10.3389/fmed.2023.1188038. eCollection 2023.
Keratinocyte Carcinomas (KC), including basal cell and cutaneous squamous cell carcinomas, are the most common skin cancers in Fitzpatrick phototype I-III individuals, while melanoma is one of the deadliest skin cancer types. The incidence of both melanoma and KC is increasing in Russia. KCs' incidence increases from north-to-south across the Russian Federation. In contrast, while melanoma's incidence increases from north-to-south in the eastern part of the country, in the west of Russia a reverse latitude gradient trend is noted, where northern more affluent regions of Russia display higher rates of melanoma than the southern jurisdictions. Furthermore, our detailed analysis of incidence by jurisdiction highlights that affluent northern capital cities have higher rates of melanoma than the surrounding regions. The observed melanoma incidence trends in the western portion of Russia are similar to the findings in the western Europe and opposite of the findings in Canada.
角质形成细胞癌（KC），包括基底细胞癌和皮肤鳞状细胞癌，是菲茨帕特里克皮肤分型I - III人群中最常见的皮肤癌，而黑色素瘤是最致命的皮肤癌类型之一。在俄罗斯，黑色素瘤和KC的发病率都在上升。KC的发病率在俄罗斯联邦境内从北向南递增。相比之下，黑色素瘤的发病率在该国东部从北向南上升，而在俄罗斯西部则呈现出相反的纬度梯度趋势，俄罗斯北部较富裕地区的黑色素瘤发病率高于南部地区。此外，我们按地区对发病率进行的详细分析表明，富裕的北方首都城市的黑色素瘤发病率高于周边地区。在俄罗斯西部观察到的黑色素瘤发病率趋势与西欧的研究结果相似，与加拿大相反。
