Lee M H, Waxman M, Gillooley J F
Dis Colon Rectum. 1986 Jun;29(6):413-6. doi: 10.1007/BF02555064.
Two homosexual men presented with primary malignant lymphomas of the anorectum. Each patient presented with a painful mass, diagnosed by biopsy and immunologic cell marker studies. One patient, who had a reversed T4/T8 cell ratio, developed a local relapse of the tumor 11 months after radiotherapy, and Pneumocystis carinii pneumonia. The other patient, with a normal T4/T8 ratio, remained lymphoma-free and without evidence of opportunistic infection 25 months after combined chemotherapy and radiotherapy. Anorectal pathologic findings in homosexual men includes proctitis, inflammatory stricture, fissure, or anal warts. Malignant anorectal diseases, such as Kaposi's sarcoma, and cloacogenic or squamous cell carcinomas have been described in homosexual men. Primary malignant lymphoma of the anorectum is rare in both the homosexual and general populations.
两名同性恋男性患有原发性直肠恶性淋巴瘤。每位患者均表现为疼痛性肿块，经活检和免疫细胞标志物研究确诊。其中一名患者T4/T8细胞比值倒置，放疗后11个月出现肿瘤局部复发，并发生卡氏肺孢子虫肺炎。另一名患者T4/T8比值正常，在联合化疗和放疗后25个月无淋巴瘤复发迹象，也无机会性感染证据。同性恋男性的肛肠病理表现包括直肠炎、炎性狭窄、肛裂或肛门疣。同性恋男性中曾有恶性肛肠疾病的报道，如卡波西肉瘤、泄殖腔源性癌或鳞状细胞癌。原发性直肠恶性淋巴瘤在同性恋人群和普通人群中均较为罕见。
