Bioplantas Centre, Universidad de Ciego de Ávila Máximo Gómez Báez, Ciego de Ávila, Cuba.
bLaboratory of Microbiology, Parasitology and Hygiene (LMPH), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium.
Nat Prod Res. 2024 Oct;38(19):3301-3310. doi: 10.1080/14786419.2023.2244132. Epub 2023 Aug 7.
The investigation of natural alternatives to conventional fungicides is of imminent need. (Britton & P. Wilson) Bisse is a Cuban endemic plant species belonging to the Myrtaceae family. The objective of the present study was to perform a bioassay-guided fractionation to explore the potential of extracts and fractions from leaves against a panel of fungal plant pathogens. The total extract was confirmed to have good antifungal activity against (IC = 4.86 µg/mL) and moderate activity against (IC = 352.40 µg/mL) and (IC = 427.38 µg/mL) and fungicidal effect against . Five compounds belonging to the class of phloroglucinol dimers were tentatively characterized by UHPLC-HRMS and reported for the first time in and the genus Mosiera. These results suggest the potential of total extract as a natural antifungal product for the control of diseases in agriculture.
迫切需要研究天然替代品来替代传统的杀菌剂。（Britton & P. Wilson）Bisse 是古巴特有的一种植物物种，属于桃金娘科。本研究的目的是进行生物活性导向的分段，以探索叶提取物和馏分对一系列真菌植物病原体的潜在作用。总提取物被证实对（IC=4.86µg/mL）具有良好的抗真菌活性，对（IC=352.40µg/mL）和（IC=427.38µg/mL）具有中度活性，对具有杀菌作用。通过 UHPLC-HRMS 初步鉴定出 5 种属于间苯三酚二聚体类的化合物，这是首次在 和 Mosiera 属中报道。这些结果表明，总提取物作为一种天然抗真菌产品，具有控制农业病害的潜力。
