Ren Kehui, Liu Hui, Wang Yujuan, Zhang Wen, Yang Ting, Xu Lili
X'ian Medical College，Xi'an，710000，China.
Department of Otolaryngology Head and Neck Surgery，Shaanxi Provincial People's Hospital.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2023 Jul;37(7):582-587. doi: 10.13201/j.issn.2096-7993.2023.07.014.
Tinnitus refers to the perception of abnormal sound in the absence of external sound stimulation. It can have an impact on a person's mood, memory, attention, and mental state, although the mechanism of tinnitus is still unclear. In recent years, the research on the central neural mechanism of tinnitus has attracted the attention of scholars.Functional magnetic resonance imaging （fMRI）,as an effective imaging technology, has been actively employed in this field. This paper provides a systematic summary of studies on the central neural mechanism of tinnitus by fMRI in recent years,revealed the changes of functional connections among tinnitus-related neural networks,such as auditory network,limbic system,default mode network and salience network. The central neural mechanism of tinnitus involves multiple networks that interact with each other. By understanding this mechanism, we hope to develop more targeted prevention and treatment strategies to help patients alleviate long-term tinnitus.
耳鸣是指在没有外部声音刺激的情况下感知到异常声音。尽管耳鸣的机制尚不清楚，但它会对人的情绪、记忆、注意力和精神状态产生影响。近年来，耳鸣的中枢神经机制研究引起了学者们的关注。功能磁共振成像（fMRI）作为一种有效的成像技术，已在该领域得到积极应用。本文对近年来利用fMRI研究耳鸣中枢神经机制的相关研究进行了系统总结，揭示了耳鸣相关神经网络（如听觉网络、边缘系统、默认模式网络和突显网络）之间功能连接的变化。耳鸣的中枢神经机制涉及多个相互作用的网络。通过了解这一机制，我们希望制定更具针对性的预防和治疗策略，以帮助患者缓解长期耳鸣。
