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根治性膀胱切除术后单脐下小切口行双侧皮肤输尿管造口术的疗效分析。

Analysis of the efficacy of a single subumbilical stoma for bilateral cutaneous ureterostomy after radical cystectomy.

机构信息

Department of Urology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

Department of Urology, Changshu No. 2 People's Hospital, Changshu, Jiangsu, China.

出版信息

Eur J Med Res. 2023 Aug 7;28(1):273. doi: 10.1186/s40001-023-01250-z.

Abstract

BACKGROUND

Radical cystectomy and urinary diversion are the standard surgical treatments for patients with muscle-invasive or high-risk, or recurrent non-muscle-invasive bladder cancer. Although this approach significantly prolongs patient survival, it can lead to postoperative complications. This study aims to compare the efficacy and complications of bilateral cutaneous ureterostomy with a single subumbilical stoma to those of cutaneous ureterostomy with two stomas and an ileal conduit as a means of urinary diversion after radical cystectomy. The findings of this study will provide valuable information for healthcare providers in selecting the appropriate urinary diversion method for their patients.

METHODS

The clinical data for 108 patients who received bilateral cutaneous ureterostomy with a single subumbilical stoma (ureterostomy with a single stoma group), cutaneous ureterostomy with two stomas (ureterostomy with two stomas group), or an ileal conduit (ileal conduit group) after radical cystectomy were retrospectively analysed. The operative time, pathological stage, survival status, perioperative complication rate, rate of successful first extubation, rehospitalization rate at 6 months after surgery,ostomy-related medical costs,and postoperative quality of life were compared between the three groups of patients.

RESULTS

A significant difference in the operative time was found between the three groups (P = 0.001). No significant differences in pathological stage, survival status, perioperative complication rate, rehospitalization rate at 6 months after surgery, or bladder cancer index (BCI) score were identified among the three groups. The difference in the successful first extubation rate between the three groups of patients was significant (P = 0.001). Significant differences in ostomy-related medical costs were observed among the three groups of patients (P = 0.006).

CONCLUSION

A single subumbilical stoma for bilateral cutaneous ureterostomy after radical cystectomy may result in shorter surgery time, increased success rates for initial catheter removal, and lower medical expenses. However, to confirm these findings, further prospective randomized clinical trials are necessary.

摘要

背景

根治性膀胱切除术和尿流改道是肌层浸润性或高危、或复发性非肌层浸润性膀胱癌患者的标准手术治疗方法。虽然这种方法显著延长了患者的生存时间,但它会导致术后并发症。本研究旨在比较双侧皮肤输尿管造口术联合单个脐下造口与皮肤输尿管造口术联合两个造口和回肠导管作为根治性膀胱切除术后尿流改道的疗效和并发症。本研究的结果将为医疗保健提供者为患者选择合适的尿流改道方法提供有价值的信息。

方法

回顾性分析 108 例接受双侧皮肤输尿管造口术联合单个脐下造口(单造口组)、皮肤输尿管造口术联合两个造口(双造口组)或回肠导管(回肠导管组)的患者的临床资料。比较三组患者的手术时间、病理分期、生存状况、围手术期并发症发生率、首次成功拔管率、术后 6 个月再入院率、造口相关医疗费用和术后生活质量。

结果

三组患者的手术时间差异有统计学意义(P = 0.001)。三组患者的病理分期、生存状况、围手术期并发症发生率、术后 6 个月再入院率和膀胱肿瘤指数(BCI)评分差异均无统计学意义。三组患者首次成功拔管率差异有统计学意义(P = 0.001)。三组患者造口相关医疗费用差异有统计学意义(P = 0.006)。

结论

根治性膀胱切除术后双侧皮肤输尿管造口术联合单个脐下造口可缩短手术时间,提高初始导管拔除成功率,降低医疗费用。然而,为了证实这些发现,需要进一步的前瞻性随机临床试验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a03/10405402/695011bc5a06/40001_2023_1250_Fig1_HTML.jpg

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