Department of Health Policy Management, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, and Shanghai Bluecross Medical Science Institute, Shanghai, The People's Republic of China; Institute for Hospital Management, Tsing Hua University, Shenzhen Campus, The People's Republic of China.
Gusu District Health Supervision Institute, Suzhou, Jiangsu, The People's Republic of China.
Health Phys. 2023 Nov 1;125(5):332-337. doi: 10.1097/HP.0000000000001722. Epub 2023 Aug 7.
Workers are frequently exposed to the occupational hazards of ionizing radiation and noise. Co-exposure to these hazards is not well understood in terms of their physiological effects. The aim of this study was to investigate the physiological effects of co-exposure to ionizing radiation and noise within the occupational limit. This study extracted the physical examination parameters of workers who met the screening criteria from the occupational health surveillance database. The workers were divided into three groups: the co-exposure (COE) group, the ionizing radiation exposure (ION) group, and the non-exposure (NON) group. The age and sex of the three groups were matched with a sample size ratio of 1:3:3. The physical examination parameters of the three groups of workers were compared. The results showed that there was no significant difference in blood pressure and blood biochemical parameters among the three groups. The COE group had higher levels of free triiodothyronine than the ION group, but there was no difference with the NON group. Moreover, the COE group had lower levels of free tetraiodothyronine than the ION group and the NON group. There was no significant difference in thyroid stimulating hormone, total triiodothyronine, and total tetraiodothyronine among the three groups. Additionally, the number of white blood cells of the COE group was lower than that of ION group and NON group. This study suggests that co-exposure to low-dose ionizing radiation and noise can cause alterations in thyroid hormone and peripheral white blood cells. These alterations are different from those observed after single exposure to low-dose ionizing radiation and require further research.
工人经常接触到电离辐射和噪声等职业危害。对于这些危害在生理效应方面的共同暴露，人们还了解甚少。本研究旨在探讨职业接触限值内电离辐射和噪声共同暴露的生理效应。本研究从职业健康监护数据库中提取符合筛选标准的工人的体检参数。工人被分为三组：共同暴露（COE）组、电离辐射暴露（ION）组和非暴露（NON）组。三组的年龄和性别与样本量比为 1:3:3 相匹配。比较三组工人的体检参数。结果表明，三组工人的血压和血液生化参数无显著差异。COE 组游离三碘甲状腺原氨酸水平高于 ION 组，但与 NON 组无差异。此外，COE 组游离四碘甲状腺原氨酸水平低于 ION 组和 NON 组。三组间甲状腺刺激激素、总三碘甲状腺原氨酸和总四碘甲状腺原氨酸无显著差异。此外，COE 组的白细胞计数低于 ION 组和 NON 组。本研究表明，低剂量电离辐射和噪声的共同暴露会导致甲状腺激素和外周白细胞发生变化。这些变化与单次低剂量电离辐射暴露后的变化不同，需要进一步研究。
