Infectious and Tropical Diseases Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Department of Parasitology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
J Med Case Rep. 2023 Aug 9;17(1):352. doi: 10.1186/s13256-023-04074-x.
Leishmaniasis is a rare infectious disease observed in subtropical and tropical areas. This disease that demonstrates different clinical characteristics is caused by intracellular Leishmania protozoan. One of the important countries facing the incidence of this infectious disease is Iran. Recently, human immunodeficiency virus-Leishmania coinfection has been indicated in Iran.
In the present case report, we show an atypical case of severe visceral leishmaniasis in a 52-year-old Iranian-Arab male with positive human immunodeficiency virus status. Leishmaniasis was detected by node biopsy and subsequently histopathology evaluations and confirmed by molecular methods.
The current study was the first report of an atypical case of a patient with Leishmania-human immunodeficiency virus coinfection in southwestern Iran, which was not responsive to the treatment. Therefore, the health authorities should be aware of these reports, which require permanent clinical follow-up of the patients as well as effective treatments.
利什曼病是一种在亚热带和热带地区观察到的罕见传染病。这种具有不同临床特征的疾病是由内阿米巴原虫引起的。伊朗是面临这种传染病发病率的重要国家之一。最近，伊朗已表明存在人类免疫缺陷病毒-利什曼原虫合并感染。
在本病例报告中，我们展示了一名 52 岁的伊朗阿拉伯男性的一例不典型严重内脏利什曼病，该男性人类免疫缺陷病毒检测结果呈阳性。利什曼病通过淋巴结活检以及随后的组织病理学评估和分子方法得到证实。
本研究首次报道了伊朗西南部一例不典型的利什曼病-人类免疫缺陷病毒合并感染病例，该病例对治疗无反应。因此，卫生当局应该意识到这些报告，这需要对患者进行永久性的临床随访和有效的治疗。
