Naeem Hafsa, Ullah Kaleem, Ochani Sidhant, Naeem Khadija, Ahmad Hafiz B, Hasibuzzaman Md Al
Department of Medicine, Dow International Medical College, Karachi.
Department of Liver Transplantation, Pir Abdul Qadir Shah Jeelani Institute of Medical Sciences, Gambat.
Ann Med Surg (Lond). 2023 Jul 3;85(8):4187-4189. doi: 10.1097/MS9.0000000000000960. eCollection 2023 Aug.
Neonatal jaundice is a common illness that affects around 80% of preterm and 50-60% of full-term newborn infants. It is one of the most common causes of neonatal death. Neonatal jaundice may be physiological or pathological. Physiologic jaundice is far more common than pathologic jaundice and accounts for most hyperbilirubinemia. Physiologic jaundice in neonates is due to greater hemoglobin breakdown compared to bilirubin clearance. While pathological jaundice occurs due to various infections, drug toxicity, inborn enzyme deficiencies, Rhesus fetal-maternal incompatibility, hypothyroidism, and congenital biliary duct obstruction diseases. In many parts of the world, midwives, and nurses perform spontaneous vaginal deliveries and they only rely on visual screening for neonatal jaundice. However, this is not reliable, especially for newborns having darker skin. Educating the mothers on screening for early detection of neonatal jaundice and seeking medical treatment in a country like Pakistan, which is considered a high-risk population, is crucial. Also, as most females give birth at home, hence, midwives' knowledge about neonatal jaundice also needs to be improved.
新生儿黄疸是一种常见疾病,约80%的早产儿和50 - 60%的足月儿会受其影响。它是新生儿死亡的最常见原因之一。新生儿黄疸可能是生理性的或病理性的。生理性黄疸远比病理性黄疸常见,并且是大多数高胆红素血症的原因。新生儿生理性黄疸是由于血红蛋白分解比胆红素清除更多。而病理性黄疸则是由各种感染、药物毒性、先天性酶缺乏、恒河猴母婴血型不合、甲状腺功能减退以及先天性胆管阻塞疾病引起的。在世界许多地方,助产士和护士进行自然阴道分娩,他们仅依靠视觉筛查新生儿黄疸。然而,这并不可靠,尤其是对于皮肤较黑的新生儿。在像巴基斯坦这样被视为高风险人群的国家,教育母亲进行新生儿黄疸早期检测的筛查并寻求医疗救治至关重要。此外,由于大多数女性在家分娩,因此,助产士关于新生儿黄疸的知识也需要提高。