Chi Honggang, Qiu Yunqi, Ye Xiaoqing, Shi Jielin, Li Ziyi
The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, China.
The Second Clinical Medical College, Guangdong Medical University, Dongguan, China.
Front Bioeng Biotechnol. 2023 Jul 24;11:1239183. doi: 10.3389/fbioe.2023.1239183. eCollection 2023.
In recent years, hydrogel microsphere has attracted much attention due to its great potential in the field of skin repair. This paper reviewed the recent progress in the preparation strategy of hydrogel microsphere and its application in skin repair. In this review, several preparation methods of hydrogel microsphere were summarized in detail. In addition, the related research progress of hydrogel microspheres for skin repair was reviewed, and focused on the application of bioactive microspheres, antibacterial microspheres, hemostatic microspheres, and hydrogel microspheres as delivery platforms (hydrogel microspheres as a microcarrier of drugs, bioactive factors, or cells) in the field of skin repair. Finally, the limitations and future prospects of the development of hydrogel microspheres and its application in the field of skin repair were presented. It is hoped that this review can provide a valuable reference for the development of the preparation strategy of hydrogel microspheres and promote the application of hydrogel microspheres in skin repair.
近年来，水凝胶微球因其在皮肤修复领域的巨大潜力而备受关注。本文综述了水凝胶微球制备策略及其在皮肤修复中的应用的最新进展。在本综述中，详细总结了水凝胶微球的几种制备方法。此外，还综述了用于皮肤修复的水凝胶微球的相关研究进展，并重点介绍了生物活性微球、抗菌微球、止血微球以及作为递送平台的水凝胶微球（水凝胶微球作为药物、生物活性因子或细胞的微载体）在皮肤修复领域的应用。最后，阐述了水凝胶微球发展及其在皮肤修复领域应用的局限性和未来前景。希望本综述能为水凝胶微球制备策略的发展提供有价值的参考，并促进水凝胶微球在皮肤修复中的应用。
