Bussien J P, Gaillard R C, Nussberger J, Waeber B, Hofbauer K G, Turnill D, Brögger R, Brunner H R
Acta Endocrinol (Copenh). 1986 Jun;112(2):166-71. doi: 10.1530/acta.0.1120166.
The effect of vasopressin released during Finnish sauna on blood pressure, heart rate and skin blood flow was investigated in 12 healthy volunteers. Exposure to the hot air decrease body weight by 0.6 to 1.25 kg (mean = 0.8 kg, P less than 0.001). One hour after the end of the sauna sessions, plasma vasopressin was higher (1.7 +/- 0.2 pg/ml, P less than 0.01 mean +/- SEM) than before the sauna (1.0 +/- 0.1 pg/ml). No simultaneous change in plasma osmolality, plasma renin activity, plasma norepinephrine, epinephrine, cortisol, aldosterone, beta-endorphin and metenkephalin levels was observed. Despite the slight sauna-induced elevation in circulating vasopressin, intravenous injection of the specific vascular vasopressin antagonist d(CH2)5Tyr(Me)AVP (5 micrograms/kg) 1 h after the sauna had no effect on blood pressure, heart rate or skin blood flow. These data suggest that vasopressin released into the circulation during a sauna session reaches concentrations which are not high enough to interfere directly with vascular tone.
在12名健康志愿者中研究了芬兰桑拿期间释放的血管加压素对血压、心率和皮肤血流的影响。暴露于热空气中使体重减轻0.6至1.25千克（平均=0.8千克，P<0.001）。桑拿结束1小时后，血浆血管加压素水平（1.7±0.2皮克/毫升，P<0.01，均值±标准误）高于桑拿前（1.0±0.1皮克/毫升）。未观察到血浆渗透压、血浆肾素活性、血浆去甲肾上腺素、肾上腺素、皮质醇、醛固酮、β-内啡肽和甲硫氨酸脑啡肽水平同时发生变化。尽管桑拿导致循环血管加压素略有升高，但在桑拿1小时后静脉注射特异性血管加压素拮抗剂d(CH2)5Tyr(Me)AVP（5微克/千克）对血压、心率或皮肤血流没有影响。这些数据表明，桑拿期间释放到循环中的血管加压素达到的浓度不足以直接干扰血管张力。
