二价 mRNA-1273.214 疫苗对 SARS-CoV-2 奥密克戎 XBB*感染的有效性。
Bivalent mRNA-1273.214 vaccine effectiveness against SARS-CoV-2 omicron XBB* infections.
机构信息
Infectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Cornell University, PO Box 24144, Doha, Qatar.
Departments of Mathematics, Statistics, and Physics, and of Biomedical Science, and of Public Health, Qatar University, PO Box 2713, Doha, Qatar.
出版信息
J Travel Med. 2023 Sep 5;30(5). doi: 10.1093/jtm/taad106.
Effectiveness of the 50-μg mRNA-1273.214 bivalent vaccine against SARS-CoV-2 infection was modest at 25% in a matched, retrospective, cohort study in Qatar comparing infection incidence in the bivalent cohort to that in the national no-recent-vaccination resident cohort. XBB* immune evasion, immune imprinting effects, or both, may explain findings.
在卡塔尔进行的一项匹配的回顾性队列研究中，50μg mRNA-1273.214 二价疫苗对 SARS-CoV-2 感染的有效性为 25%，该研究将二价疫苗组的感染发生率与全国无近期接种疫苗的居民队列进行了比较。XBB*免疫逃逸、免疫印记效应或两者兼而有之，可能解释了这些发现。
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