Youssef Randa, Emad Nourhan, Mogawer Rania M
Dermatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Dermatol Pract Concept. 2023 Jul 1;13(3):e2023186. doi: 10.5826/dpc.1303a186.
There are diverse assessment tools for vitiligo, with no standardized approach that helps unify treatment outcome measures. Thus, comparing different treatment modalities and developing evidence-based recommendations for vitiligo management has been quite challenging.
We compared the most commonly used tools assessing both vitiligo activity and extent, namely, Vitiligo Disease Activity Score (VIDA) and Vitiligo Area and Severity Index (VASI) score to their newly developed counterparts, namely, Vitiligo Extent Score Plus (VES plus) and Vitiligo Signs of Activity score (VSAS), to provide insights that would help set recommendations for a unified outcome assessment protocol for vitiligo patients.
Thirty-six active non-segmental vitiligo cases were recruited, 30 of whom completed 48 sessions of narrow band ultraviolet B (NB-UVB). Patients were assessed for both extent and activity both before and after treatment with NB-UVB. Scores were correlated. Additionally, VES plus was assessed for its reliability in comparison to VASI score.
Both extent (VASI and VES plus) and activity scores (VIDA and VSAS) showed significant improvement following treatment. Additionally, VES plus and VASI were positively correlating both before and after treatment as well as their percent change. Furthermore, VES plus proved as reliable as VASI. Regarding activity scores, total, hypochromic and Koebner VSAS only correlated with VIDA following treatment. Confetti VSAS neither correlated with VIDA before nor after treatment.
VES plus and VASI scores have proven of comparable reliability. While examination-based VSAS score comes as an additive tool to the history-based VIDA score.
白癜风有多种评估工具，但没有标准化方法来统一治疗效果衡量标准。因此，比较不同治疗方式并制定基于证据的白癜风管理建议颇具挑战性。
我们将评估白癜风活动度和范围最常用的工具，即白癜风疾病活动评分（VIDA）和白癜风面积及严重程度指数（VASI）评分，与其新开发的对应工具，即白癜风范围评分升级版（VES plus）和白癜风活动迹象评分（VSAS）进行比较，以提供有助于为白癜风患者制定统一结局评估方案建议的见解。
招募了36例活动性非节段性白癜风患者，其中30例完成了48次窄谱中波紫外线（NB - UVB）治疗。在NB - UVB治疗前后对患者的范围和活动度进行评估。对评分进行相关性分析。此外，将VES plus与VASI评分相比评估其可靠性。
治疗后范围（VASI和VES plus）及活动度评分（VIDA和VSAS）均显示出显著改善。此外，VES plus和VASI在治疗前后及其变化百分比方面均呈正相关。而且，VES plus与VASI可靠性相当。关于活动度评分，治疗后总、色素减退和同形反应性VSAS仅与VIDA相关。纸屑样VSAS在治疗前后均与VIDA不相关。
VES plus和VASI评分已证明具有相当的可靠性。基于检查的VSAS评分是基于病史的VIDA评分的补充工具。
