Awal Guneet, Kaur Navleen, Singh Guramrit, Sharma Nishant
Department of Dermatology,Venereology and Leprosy, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, India.
Department of Community Medicine, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, India.
Dermatol Pract Concept. 2024 Apr 1;14(2):e2024075. doi: 10.5826/dpc.1402a75.
Assessment of disease severity of vitiligo is exigent as it is a psychosomatic ailment. VIDA (vitiligo disease activity score) and VASI (vitiligo area severity index) were previously used for this evaluation. Recently, the introduction of two vitiligo specific tools, vitiligo impact scale (VIS)-22 and Vitiligo Quality of Life Index (VitiQoL) has aided in assessing the quality of life (QOL) in a pertinent manner.
To measure the QOL in vitiligo using disease specific indices (VitiQoL and VIS-22), to assess their relationship with disease severity (VASI and VIDA) and to determine the correlation between QOL scores (VIS-22 and VitiQoL).
This observational cross-sectional study included 195 patients with vitiligo, and their disease severity was calculated using VASI and VIDA scoring. Patients were asked to fill questionnaires for assessing the QOL using validated tools i.e. VIS-22 and VitiQoL.
Significant correlation was demonstrated between both QOL scores and VASI score (P value 0.001) with slightly higher values for VitiQoL (r = 0.824) than with VIS 22 (r = 0.693). Both scores exhibited a significant association with VIDA score (P value < 0.001). Moreover, statistically significant correlation was found between VIS-22 and VitiQoL, thereby proving the concordance between these scores.
The study infers that QOL seemed to be remarkably dependent on the clinical severity scores and that higher disease activity corresponds to poorer QOL. It is imperative to precisely assess burden of vitiligo and the impairments caused by it in order to aid multi-modality management and allow more standardized research.
白癜风是一种身心疾病，因此对其疾病严重程度进行评估非常迫切。白癜风疾病活动度评分（VIDA）和白癜风面积严重程度指数（VASI）此前被用于此项评估。最近，两种白癜风特异性工具——白癜风影响量表（VIS）-22和白癜风生活质量指数（VitiQoL）的引入，有助于以恰当的方式评估生活质量（QOL）。
使用疾病特异性指标（VitiQoL和VIS-22）测量白癜风患者的生活质量，评估它们与疾病严重程度（VASI和VIDA）的关系，并确定生活质量评分（VIS-22和VitiQoL）之间的相关性。
这项观察性横断面研究纳入了195例白癜风患者，并使用VASI和VIDA评分计算他们的疾病严重程度。要求患者使用经过验证的工具即VIS-22和VitiQoL填写评估生活质量的问卷。
两种生活质量评分与VASI评分之间均显示出显著相关性（P值0.001），VitiQoL的相关性值（r = 0.824）略高于VIS 22（r = 0.693）。两种评分与VIDA评分均呈现显著相关性（P值<0.001）。此外，在VIS-22和VitiQoL之间发现了具有统计学意义的相关性，从而证明了这些评分之间的一致性。
该研究推断，生活质量似乎明显取决于临床严重程度评分，且疾病活动度越高，生活质量越差。为了辅助多模式管理并实现更标准化的研究，精确评估白癜风的负担及其造成的损害至关重要。
