Department of Chemistry and Biochemistry, California State University, Los Angeles, 5151 State University Drive, Los Angeles, California 90032, United States.
ACS Appl Bio Mater. 2023 Aug 21;6(8):3052-3065. doi: 10.1021/acsabm.3c00391. Epub 2023 Aug 10.
The swift and deadly spread of infectious diseases, alongside the rapid advancement of scientific technology in the past several centuries, has led to the invention of various methods for protecting people from infection. In recent years, a class of crystalline porous materials, metal-organic frameworks (MOFs), has shown great potential in constructing defense systems against infectious diseases. This review addresses current approaches to combating infectious diseases through the utilization of MOFs in vaccine development, antiviral and antibacterial treatment, and personal protective equipment (PPE). Along with an updated account of MOFs used for designing defense systems against infectious diseases, directions are also suggested for expanding avenues of current MOF research to develop more effective approaches and tools to prevent the widespread nature of infectious diseases.
传染病的迅速和致命传播，以及过去几个世纪科学技术的快速进步，导致了各种保护人们免受感染的方法的发明。近年来，一类结晶多孔材料，金属-有机骨架（MOFs），在构建针对传染病的防御系统方面显示出巨大的潜力。这篇综述讨论了通过在疫苗开发、抗病毒和抗菌治疗以及个人防护设备（PPE）中利用 MOFs 来对抗传染病的当前方法。除了更新用于设计针对传染病的防御系统的 MOFs 之外，还为扩展当前 MOF 研究的途径以开发更有效的方法和工具来预防传染病的广泛传播提出了建议。
