Department of Otorhinolaryngology- Head and Neck Surgery, Hospital Universitari de Tarragona Joan XXIII, Doctor Mallafre Guasch 4, 43005, Tarragona, Catalonia, Spain.
Institut d'Investigació Sanitària Pere Virgili, Tarragona, Catalonia, Spain.
Curr Allergy Asthma Rep. 2023 Oct;23(10):567-578. doi: 10.1007/s11882-023-01104-y. Epub 2023 Aug 10.
Mechanical nasal obstruction (MNO) is a prevalent condition with a high impact on patient's quality-of-life (QoL) and socio-economic burden. The aim of this study was to determine the usefulness of both subjective and objective criteria in the appropriate management of MNO, either alone or associated to upper airway inflammatory diseases such as allergic rhinitis (AR) or chronic rhinosinusitis with nasal polyps (CRSwNP).
A long debate persists about the usefulness of subjective and objective methods for making decisions on the management of patients with nasal obstruction. Establishing standards and ranges of symptom scales and questionnaires is essential to measure the success of an intervention and its impact on QoL. To our knowledge this is the first real-life study to describe the management of MNO using both subjective and objective criteria in MNO isolated or associated to upper airway inflammatory diseases (AR or CRSwNP). Medical treatment (intranasal corticosteroids) has a minor but significant improvement in MNO subjective outcomes (NO, NOSE, and CQ7) with no changes in loss of smell and objective outcomes. After surgery, all MNO patients reported a significant improvement in both subjective and objective outcomes, this improvement being higher in CRSwNP. We concluded that in daily clinical practice, the therapeutic recommendation for MNO should be based on both subjective and objective outcomes, nasal corrective surgery being the treatment of choice in MNO, either isolated or associated to upper airway inflammatory diseases, AR or CRSwNP.
机械性鼻阻塞(MNO)是一种普遍存在的疾病,对患者的生活质量(QoL)和社会经济负担有很大影响。本研究的目的是确定主观和客观标准在 MNO 治疗中的作用,无论是单独使用还是与上气道炎症性疾病(如过敏性鼻炎(AR)或伴有鼻息肉的慢性鼻-鼻窦炎(CRSwNP))相关联。
关于使用主观和客观方法来决定鼻阻塞患者治疗的问题,一直存在着长期的争论。建立症状量表和问卷的标准和范围对于衡量干预的成功及其对 QoL 的影响至关重要。据我们所知,这是第一项真实描述使用主观和客观标准来管理孤立性 MNO 或与上气道炎症性疾病(AR 或 CRSwNP)相关联的 MNO 的研究。药物治疗(鼻内皮质类固醇)对 MNO 主观结局(NO、NOSE 和 CQ7)有较小但有统计学意义的改善,而嗅觉丧失和客观结局没有变化。手术后,所有 MNO 患者的主观和客观结局均有显著改善,在 CRSwNP 中改善更为明显。我们得出结论,在日常临床实践中,MNO 的治疗建议应基于主观和客观结局,鼻腔矫正手术是 MNO 的首选治疗方法,无论是孤立性还是与上气道炎症性疾病(AR 或 CRSwNP)相关联。