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开放式与内镜下鼻中隔成形术技术:系统评价与荟萃分析

Open versus endoscopic septoplasty techniques: A systematic review and meta-analysis.

作者信息

Hong Chris J, Monteiro Eric, Badhiwala Jetan, Lee John, de Almeida John R, Vescan Allan, Witterick Ian J

机构信息

Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.

出版信息

Am J Rhinol Allergy. 2016 Nov 1;30(6):436-442. doi: 10.2500/ajra.2016.30.4366.

Abstract

BACKGROUND

Septal deviation is a condition of high prevalence, which ranges from 22% in newborns to 90% in adults. Surgical intervention is frequently considered in the management of patients with symptoms. Although many surgeons prefer either the endoscopic or the open approach to septoplasty, there is an ongoing debate regarding comparative outcomes between the two approaches.

OBJECTIVE

The purpose of this study was to systematically review the literature and provide pooled summary estimates to evaluate the efficacy and safety of open versus endoscopic septoplasty techniques.

METHODS

This study was registered with PROSPERO (CRD42014010730). MEDLINE, EMBASE, Google Scholar, CINAHL, Web of Science, and The Cochrane Central Registry for Randomized Trials were searched for relevant studies by using the following keywords in varying combinations: "nasal septum," "nasal obstruction," "nasal cartilages," "nose," "nose diseases," "surgery," "nasal/septal deviation," and "septoplasty." All the studies that compared open versus endoscopic septoplasty techniques for the management of symptomatic septal deviation were considered. Two reviewers independently extracted data by using a preestablished extraction form and performed quality assessment by using the Jadad and Newcastle Ottawa Scales. Weighted pooled estimates were calculated and reported, along with relative risks and 95% confidence intervals.

RESULTS

Fourteen studies met our inclusion criteria. When comparing open versus endoscopic septoplasty techniques, there was significant improvement in postoperative symptoms (i.e., nasal obstruction, headaches) (p < 0.05) in the endoscopic septoplasty group. There also were significantly fewer complications associated with the endoscopic septoplasty technique (p < 0.05). Based on the quality assessment, included studies were deemed at a moderate-to-high risk of bias.

CONCLUSION

Our analysis indicated that endoscopic septoplasty may have some advantages over open septoplasty. However, our findings should be taken with caution given the poor quality of included studies.

摘要

背景

鼻中隔偏曲是一种高发性疾病,在新生儿中的发生率为22%,在成年人中则高达90%。对于有症状的患者,手术干预常常被纳入治疗方案。尽管许多外科医生更倾向于采用内镜或开放式鼻中隔成形术,但关于这两种手术方式的比较结果仍存在争议。

目的

本研究旨在系统回顾文献,并提供汇总的总结性估计值,以评估开放式与内镜下鼻中隔成形术的疗效和安全性。

方法

本研究已在国际前瞻性系统评价注册库(PROSPERO,注册号:CRD42014010730)登记。通过使用以下关键词的不同组合,对MEDLINE、EMBASE、谷歌学术、护理学与健康领域数据库(CINAHL)、科学引文索引(Web of Science)以及Cochrane随机对照试验中心注册库进行检索,以查找相关研究:“鼻中隔”“鼻阻塞”“鼻软骨”“鼻子”“鼻疾病”“手术”“鼻/鼻中隔偏曲”以及“鼻中隔成形术”。所有比较开放式与内镜下鼻中隔成形术治疗有症状鼻中隔偏曲的研究均被纳入。两名研究者使用预先制定的提取表独立提取数据,并使用Jadad评分量表和纽卡斯尔-渥太华量表进行质量评估。计算并报告加权汇总估计值以及相对风险和95%置信区间。

结果

14项研究符合我们的纳入标准。在内镜下鼻中隔成形术组中,与开放式鼻中隔成形术相比,术后症状(即鼻阻塞、头痛)有显著改善(p<0.05)。内镜下鼻中隔成形术技术相关的并发症也显著更少(p<0.05)。基于质量评估,纳入的研究被认为存在中度至高偏倚风险。

结论

我们的分析表明,内镜下鼻中隔成形术可能比开放式鼻中隔成形术具有一些优势。然而,鉴于纳入研究的质量较差,我们的研究结果应谨慎对待。

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