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老年胰腺癌患者的外科治疗

Surgical management for elderly patients with pancreatic cancer.

作者信息

Kim Sun-Whe

机构信息

Department of Surgery, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong, Korea.

出版信息

Ann Surg Treat Res. 2023 Aug;105(2):63-68. doi: 10.4174/astr.2023.105.2.63. Epub 2023 Aug 1.

DOI:10.4174/astr.2023.105.2.63
PMID:37564946
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10409631/
Abstract

Pancreatic cancer, one of the diseases of the elderly, has dismal prognosis, demanding major surgery with high risk and life quality problems, especially in the elderly. Therefore, treatment selection, whether or not to undergo surgery, preoperative risk assessment, and perioperative management of the elderly are becoming critical issues. Although the elderly are expected to have higher morbidity and mortality and lower long-term survival outcomes, surgery is becoming safer over time. Appropriate surgical indication selection, patient-centered decision-making, adequate prehabilitation and postoperative geriatric care are expected to improve surgical outcomes in the elderly. Surgeons must have the concept of geriatric care, and efforts based on institutional systems and academic societies are required. If well selected and prepared, the same surgical principle as non-elderly patients can be applied to elderly patients. In this paper, the surgical treatment of elderly patients with pancreatic cancer is reviewed.

摘要

胰腺癌是老年人易患的疾病之一,预后很差,需要进行高风险的大手术,且存在生活质量问题,在老年人中尤为如此。因此,治疗方案的选择、是否进行手术、术前风险评估以及老年人的围手术期管理正成为关键问题。尽管老年人预计发病率和死亡率更高,长期生存结果更低,但随着时间的推移,手术正变得越来越安全。选择合适的手术指征、以患者为中心的决策、充分的术前康复和术后老年护理有望改善老年人的手术效果。外科医生必须具备老年护理的理念,并且需要基于机构系统和学术团体做出努力。如果选择得当并做好准备,适用于非老年患者的相同手术原则也可应用于老年患者。本文对老年胰腺癌患者的外科治疗进行综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bbf/10409631/d468ed858cae/astr-105-63-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bbf/10409631/c199e11686b8/astr-105-63-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bbf/10409631/6ec471618e01/astr-105-63-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bbf/10409631/d468ed858cae/astr-105-63-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bbf/10409631/c199e11686b8/astr-105-63-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bbf/10409631/6ec471618e01/astr-105-63-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2bbf/10409631/d468ed858cae/astr-105-63-g003.jpg

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本文引用的文献

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HPB (Oxford). 2022 Oct;24(10):1720-1728. doi: 10.1016/j.hpb.2022.05.002. Epub 2022 May 13.
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Effect of Laparoscopic Pancreaticoduodenectomy in Elderly People: A Meta-analysis.腹腔镜胰十二指肠切除术治疗老年人的效果:一项荟萃分析。
Pancreas. 2021 Sep 1;50(8):1154-1162. doi: 10.1097/MPA.0000000000001900.
3
Treatment Paradigms for Older Adults with Pancreatic Cancer: a Nuanced Approach.
老年胰腺癌患者的治疗模式:一种细致入微的方法。
Curr Treat Options Oncol. 2021 Oct 1;22(11):104. doi: 10.1007/s11864-021-00892-7.
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Optimal management of patients with operable pancreatic head cancer: A Markov decision analysis.可切除胰头癌患者的最佳管理:马尔可夫决策分析。
J Surg Oncol. 2021 Oct;124(5):801-809. doi: 10.1002/jso.26589. Epub 2021 Jul 7.
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First Course of treatment and Prognosis of Exocrine Pancreatic Cancer in Korea from 2006 to 2017.2006 年至 2017 年韩国外分泌胰腺肿瘤的治疗方案和预后
Cancer Res Treat. 2022 Jan;54(1):208-217. doi: 10.4143/crt.2021.421. Epub 2021 May 21.
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Ann Surg Oncol. 2021 Oct;28(11):6264-6272. doi: 10.1245/s10434-021-09822-1. Epub 2021 Mar 21.
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Minimally Invasive Pancreaticoduodenectomy in Elderly Patients: Systematic Review and Meta-Analysis.老年患者的微创胰腺十二指肠切除术:系统评价和荟萃分析。
World J Surg. 2021 Apr;45(4):1186-1201. doi: 10.1007/s00268-020-05945-w. Epub 2021 Jan 17.
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