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钠限制在高血压管理中的作用。

The role of sodium restriction in the management of hypertension.

作者信息

Morgan T, Nowson C

出版信息

Can J Physiol Pharmacol. 1986 Jun;64(6):786-92. doi: 10.1139/y86-135.

Abstract

More than 50 studies have investigated the effect of altered sodium intake on blood pressure. A regression line drawn through the change in blood pressure and change in sodium intake indicates that blood pressure alters about 10 mmHg (1 mmHg = 133.322 Pa) for every 100 mmol/day alteration in sodium intake, a change similar to that observed in between-population "studies." The studies that have failed to show a change in blood pressure have usually been in people with a blood pressure less than 130/90 mmHg. Normotensive people appear to tolerate a higher intake of sodium before blood pressure rises, but if increased sufficiently, blood pressure rises in most people. Sodium restriction reduces blood pressure in people with severe hypertension, moderate hypertension and mild hypertension. It may be the cause of blood pressure increase associated with age and the reason for the higher prevalence of hypertension and vascular disease in Western communities. Sodium restriction should be used to treat people with elevated blood pressure.

摘要

超过50项研究调查了钠摄入量改变对血压的影响。通过血压变化和钠摄入量变化绘制的回归线表明,钠摄入量每改变100 mmol/天,血压大约改变10 mmHg(1 mmHg = 133.322 Pa),这一变化与在人群间“研究”中观察到的情况相似。未能显示血压变化的研究通常是在血压低于130/90 mmHg的人群中进行的。血压正常的人在血压升高之前似乎能耐受更高的钠摄入量,但如果钠摄入量充分增加,大多数人的血压会升高。钠限制可降低重度高血压、中度高血压和轻度高血压患者的血压。它可能是与年龄相关的血压升高的原因,也是西方社区高血压和血管疾病患病率较高的原因。钠限制应用于治疗血压升高的患者。

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