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钠限制在高血压管理中的作用。

The role of sodium restriction in the management of hypertension.

作者信息

Morgan T, Nowson C

出版信息

Can J Physiol Pharmacol. 1986 Jun;64(6):786-92. doi: 10.1139/y86-135.

DOI:10.1139/y86-135
PMID:3756633
Abstract

More than 50 studies have investigated the effect of altered sodium intake on blood pressure. A regression line drawn through the change in blood pressure and change in sodium intake indicates that blood pressure alters about 10 mmHg (1 mmHg = 133.322 Pa) for every 100 mmol/day alteration in sodium intake, a change similar to that observed in between-population "studies." The studies that have failed to show a change in blood pressure have usually been in people with a blood pressure less than 130/90 mmHg. Normotensive people appear to tolerate a higher intake of sodium before blood pressure rises, but if increased sufficiently, blood pressure rises in most people. Sodium restriction reduces blood pressure in people with severe hypertension, moderate hypertension and mild hypertension. It may be the cause of blood pressure increase associated with age and the reason for the higher prevalence of hypertension and vascular disease in Western communities. Sodium restriction should be used to treat people with elevated blood pressure.

摘要

超过50项研究调查了钠摄入量改变对血压的影响。通过血压变化和钠摄入量变化绘制的回归线表明,钠摄入量每改变100 mmol/天,血压大约改变10 mmHg(1 mmHg = 133.322 Pa),这一变化与在人群间“研究”中观察到的情况相似。未能显示血压变化的研究通常是在血压低于130/90 mmHg的人群中进行的。血压正常的人在血压升高之前似乎能耐受更高的钠摄入量,但如果钠摄入量充分增加,大多数人的血压会升高。钠限制可降低重度高血压、中度高血压和轻度高血压患者的血压。它可能是与年龄相关的血压升高的原因,也是西方社区高血压和血管疾病患病率较高的原因。钠限制应用于治疗血压升高的患者。

相似文献

1
The role of sodium restriction in the management of hypertension.钠限制在高血压管理中的作用。
Can J Physiol Pharmacol. 1986 Jun;64(6):786-92. doi: 10.1139/y86-135.
2
[A population study of long-term salt restriction in mild hypertensives].[轻度高血压患者长期限盐的人群研究]
Hokkaido Igaku Zasshi. 1991 Jul;66(4):492-501.
3
Hypertension treated by sodium restriction.通过限制钠摄入治疗高血压。
Med J Aust. 1981 Oct 17;2(8):396-7. doi: 10.5694/j.1326-5377.1981.tb101026.x.
4
The effect of sodium intake on the blood pressure related to age and sex.钠摄入量对与年龄和性别相关的血压的影响。
Clin Exp Hypertens A. 1983;5(1):99-118. doi: 10.3109/10641968309048813.
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Adherence to the salt restriction diet among people with mildly elevated blood pressure.轻度高血压患者对限盐饮食的依从性。
Eur J Clin Nutr. 1999 Nov;53(11):880-5. doi: 10.1038/sj.ejcn.1600869.
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Dietary sodium restriction for mild hypertension in general practice.一般医疗实践中对轻度高血压患者的膳食钠限制
Br Med J (Clin Res Ed). 1983 Feb 5;286(6363):432-6. doi: 10.1136/bmj.286.6363.432.
7
The role of sodium and potassium in the control of blood pressure.钠和钾在血压控制中的作用。
Aust N Z J Med. 1984 Aug;14(4):458-62. doi: 10.1111/j.1445-5994.1984.tb03615.x.
8
Relation between arterial pressure, dietary sodium intake, and renin system in essential hypertension.原发性高血压患者动脉血压、膳食钠摄入量与肾素系统之间的关系。
Br Med J (Clin Res Ed). 1981 Jul 11;283(6284):94-7. doi: 10.1136/bmj.283.6284.94.
9
The importance of the response of the renin-angiotensin system in determining blood pressure changes with sodium restriction.肾素-血管紧张素系统在确定限钠时血压变化中的反应的重要性。
Br J Clin Pharmacol. 1987;23 Suppl 1(Suppl 1):21S-26S. doi: 10.1111/j.1365-2125.1987.tb03119.x.
10
Double-blind randomised trial of modest salt restriction in older people.老年人适度限盐的双盲随机试验。
Lancet. 1997 Sep 20;350(9081):850-4. doi: 10.1016/S0140-6736(97)02264-2.

引用本文的文献

1
Essential hypertension: when and how to initiate treatment.原发性高血压:何时以及如何开始治疗。
Can Fam Physician. 1989 Sep;35:1821-6.
2
Salt intake, blood pressure, and cardiovascular structure.盐摄入量、血压与心血管结构。
Cardiovasc Drugs Ther. 1994 Jun;8(3):425-32. doi: 10.1007/BF00877918.
3
Essential hypertension: a sign in search of a disease.原发性高血压:一种有待明确病因的体征。
CMAJ. 1991 Apr 15;144(8):973-9.