Berényi E, Zsindely A, Fésüs L, Szegedi G, Kávai M
Cancer Lett. 1986 Aug;32(2):219-22. doi: 10.1016/0304-3835(86)90122-9.
Acid phosphatase (AP) levels have been found to be decreased in monocytes of 38 patients with Hodgkin's disease as compared to 16 healthy subjects. Low cellular AP activity was associated with the presence of active disease, stage IV and lymphocyte depletion type. Lactate dehydrogenase (LDH) was decreased in monocytes of patients but the difference did not reach statistical significance. In parallel, serum AP activities have been found to be increased in patients. There was an inverse correlation between the monocyte and serum AP levels which can be explained by assuming AP secretion from monocytes of patients in vivo.
与16名健康受试者相比，已发现38例霍奇金病患者单核细胞中的酸性磷酸酶（AP）水平降低。低细胞AP活性与活动性疾病、IV期及淋巴细胞消减型的存在相关。患者单核细胞中的乳酸脱氢酶（LDH）降低，但差异未达到统计学意义。同时，已发现患者血清AP活性升高。单核细胞和血清AP水平之间呈负相关，这可以通过假设患者单核细胞在体内分泌AP来解释。
