Kávai M, Berényi E, Zsindely A, Szegedi G, Fésüs L
Int J Cancer. 1984 Oct 15;34(4):483-5. doi: 10.1002/ijc.2910340409.
Transglutaminase activity in monocytes and serum lysozyme level were tested in 40 patients with Hodgkin's disease and were found to be significantly increased. Transglutaminase activity in monocytes from patients in a clinically active stage of the disease was higher than in clinically inactive cases of HD, and varied along with the histological subtypes. Serum lysozyme varied with the stage of the disease and with the symptomatology as well as with the histological subtype. The enzyme activities were higher before any treatment than after. A parallel increase of transglutaminase activity in monocytes and of serum lysozyme level suggests an elevated activity of the mononuclear phagocyte system in Hodgkin's disease.
对40例霍奇金病患者的单核细胞转谷氨酰胺酶活性和血清溶菌酶水平进行了检测，发现均显著升高。处于疾病临床活动期患者的单核细胞转谷氨酰胺酶活性高于霍奇金病临床非活动期患者，且随组织学亚型而变化。血清溶菌酶随疾病分期、症状以及组织学亚型而变化。酶活性在任何治疗前均高于治疗后。单核细胞中转谷氨酰胺酶活性与血清溶菌酶水平的平行升高提示霍奇金病中单核吞噬细胞系统活性增强。
