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单术者机器人辅助根治性膀胱切除术并经回肠导管行体内尿流改道术学习曲线的回顾性评估

Retrospective Evaluation of a Single Surgeon's Learning Curve of Robot-Assisted Radical Cystectomy with Intracorporeal Urinary Diversion via Ileal Conduit.

作者信息

Achermann Christof, Sauer Andreas, Cattaneo Marco, Walz Jochen, Wyler Stephen F, Kwiatkowski Maciej, Prause Lukas W

机构信息

Department of Urology, Cantonal Hospital Aarau, 5001 Aarau, Switzerland.

Department of Urology, University Hospital of Basel, University of Basel, 4001 Basel, Switzerland.

出版信息

Cancers (Basel). 2023 Jul 26;15(15):3799. doi: 10.3390/cancers15153799.

Abstract

Robot-assisted radical cystectomy with intracorporeal urinary diversion (iRARC) is increasingly being performed instead of open surgery. A criticism of this technique is the long learning curve, but limited data are available on this topic. At our center, the transition from open radical cystectomy (ORC) to iRARC began in May 2017. A retrospective analysis was conducted on the initial 53 cases of robot-assisted cystectomy with intracorporeal urinary diversion via ileal conduit, which were performed by one single surgeon. The patients were divided into four consecutive groups according to the surgeon's increasing experience, and perioperative parameters were analyzed as a surrogate for the learning curve. Over the course of the learning curve, a decline in median operation time from 415 to 361 min ( = 0.02), blood loss from 400 to 200 mL ( = 0.01), and minor complications from 71% to 15% ( = 0.02) was observed. No significant difference in overall and major complications, length of hospital stay, and total lymph node yield was shown. During the initial period of the learning curve, only the less complex cases were operated on using robotic surgery, while the more challenging ones were handled through open surgery. After experience with 28 cases, no more cystectomies were performed through open surgery. This led to an increase in operation time and length of hospital stay, as well as a higher incidence of both minor and overall complications among cases 28-40. After 40 cases, a significant decrease in these parameters was observed again. Our analysis demonstrated that operation time, blood loss, and minor complications decrease with increasing surgical experience in iRARC, while suggesting that technically challenging cases should be operated on after experience with 40 robotic cystectomies.

摘要

机器人辅助根治性膀胱切除术联合体内尿流改道术(iRARC)正越来越多地取代开放手术。对该技术的一项批评是学习曲线较长,但关于这一主题的数据有限。在我们中心,从开放根治性膀胱切除术(ORC)向iRARC的转变始于2017年5月。对由一名外科医生实施的最初53例机器人辅助膀胱切除术联合回肠通道体内尿流改道术进行了回顾性分析。根据外科医生经验的增加,将患者分为连续四组,并分析围手术期参数作为学习曲线的替代指标。在学习曲线过程中,观察到中位手术时间从415分钟降至361分钟(P = 0.02),失血量从400毫升降至200毫升(P = 0.01),轻微并发症从71%降至15%(P = 0.02)。在总体和主要并发症、住院时间和总淋巴结收获量方面未显示出显著差异。在学习曲线的初始阶段,仅对不太复杂的病例采用机器人手术,而更具挑战性的病例则通过开放手术处理。在完成28例手术的经验积累后,不再进行开放膀胱切除术。这导致手术时间和住院时间增加,以及28 - 40例病例中轻微和总体并发症的发生率更高。在完成40例手术后,再次观察到这些参数显著下降。我们的分析表明,在iRARC中,随着手术经验的增加,手术时间、失血量和轻微并发症会减少,同时表明在有40例机器人膀胱切除术经验后,应处理技术上具有挑战性的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea31/10416818/d7756c7de3a0/cancers-15-03799-g001.jpg

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