Akbulut Ayse Selenge, Akca Karpuzoglu Aysun Hatice
Department of Orthodontics, Peri Sokak Dental Clinic, 42010 Konya, Türkiye.
Department of Neurology, Medova Hospital, 42070 Konya, Türkiye.
Diagnostics (Basel). 2023 Jul 26;13(15):2482. doi: 10.3390/diagnostics13152482.
(1) The aim of this study was to perform an evaluation of the temporomandibular joint (TMJ) in patients with Parkinson's disease (PD) and present the morphological differences of the TMJ between healthy subjects and patients with PD. (2) A total of 102 Caucasian subjects were divided equally into two groups. The study group consisted of patients with PD, while the control group comprised healthy subjects. Ten parameters, including anterior joint space (AJS), superior joint space (SJS), posterior joint space (PJS), condyle head length (CHL), condylar neck width (CNW), minor axis of the condyle (MAC), long axis of the condyle (LAC), condylar axis inclination (CI), medial joint space (MJS), and lateral joint space (LJS), were measured using magnetic resonance images. The data were statistically analyzed using paired samples -test and Student's -test, with a significance level set at < 0.05. (3) In the PD group, all TMJ parameters showed a statistically significant difference between both sides of the face ( < 0.05). However, in the control group, AJS, SJS, PJS, CHL, CNW, MAC, CI, MJS, and LJS did not show a statistically significant difference between both sides of the face ( > 0.05), except for LAC ( < 0.05). The asymmetry index values of AJS, SJS, PJS, CHL, CNW, MAC, CI, MJS, and LJS demonstrated a statistically significant difference between the study and control groups ( < 0.05), except for LAC ( > 0.05). (4) Within the limitations of this retrospective study, the findings suggest that TMJ morphology and asymmetry could be associated with PD.
(1) 本研究的目的是对帕金森病（PD）患者的颞下颌关节（TMJ）进行评估，并呈现健康受试者与PD患者之间TMJ的形态学差异。(2) 总共102名白种人受试者被平均分为两组。研究组由PD患者组成，而对照组包括健康受试者。使用磁共振图像测量了10个参数，包括前关节间隙（AJS）、上关节间隙（SJS）、后关节间隙（PJS）、髁突头长度（CHL）、髁突颈宽度（CNW）、髁突短轴（MAC）、髁突长轴（LAC）、髁突轴倾斜度（CI）、内侧关节间隙（MJS）和外侧关节间隙（LJS）。数据采用配对样本t检验和学生t检验进行统计学分析，显著性水平设定为P < 0.05。(3) 在PD组中，所有TMJ参数在面部两侧之间均显示出统计学上的显著差异（P < 0.05）。然而，在对照组中，除LAC外（P < 0.05），AJS、SJS、PJS、CHL、CNW、MAC、CI、MJS和LJS在面部两侧之间未显示出统计学上的显著差异（P > 0.05）。AJS、SJS、PJS、CHL、CNW、MAC、CI、MJS和LJS的不对称指数值在研究组和对照组之间显示出统计学上的显著差异（P < 0.05），除LAC外（P > 0.05）。(4) 在这项回顾性研究的局限性范围内，研究结果表明TMJ形态和不对称可能与PD有关。
