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水凝胶中的扩散限制过程及其在药物传递到电子元件等方面的应用。

Diffusion-Limited Processes in Hydrogels with Chosen Applications from Drug Delivery to Electronic Components.

机构信息

Infochemistry Scientific Center, ITMO University, 191002 Saint Petersburg, Russia.

Laboratory of Polymer and Composite Materials "SmartTextiles", IRC-X-ray Coherent Optics, Immanuel Kant Baltic Federal University, 236041 Kaliningrad, Russia.

出版信息

Molecules. 2023 Aug 7;28(15):5931. doi: 10.3390/molecules28155931.

Abstract

Diffusion is one of the key nature processes which plays an important role in respiration, digestion, and nutrient transport in cells. In this regard, the present article aims to review various diffusion approaches used to fabricate different functional materials based on hydrogels, unique examples of materials that control diffusion. They have found applications in fields such as drug encapsulation and delivery, nutrient delivery in agriculture, developing materials for regenerative medicine, and creating stimuli-responsive materials in soft robotics and microrobotics. In addition, mechanisms of release and drug diffusion kinetics as key tools for material design are discussed.

摘要

扩散是一种关键的自然过程,在细胞的呼吸、消化和营养物质运输中起着重要作用。在这方面,本文旨在综述各种用于制造不同功能材料的扩散方法,这些材料以水凝胶为基础,是控制扩散的独特材料范例。它们已经在药物封装和输送、农业中的营养物质输送、开发再生医学材料以及在软机器人和微型机器人中创建刺激响应材料等领域得到了应用。此外,还讨论了作为材料设计关键工具的释放机制和药物扩散动力学。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f2b/10421015/2cf92ae10721/molecules-28-05931-g001.jpg

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