Polymer Science Unit, School of Materials Sciences, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India.
Soft Matter. 2020 Feb 12;16(6):1404-1454. doi: 10.1039/c9sm02127b.
In this review, we focus on the very recent developments on the use of the stimuli responsive properties of polymer hydrogels for targeted drug delivery, tissue engineering, and biosensing utilizing their different optoelectronic properties. Besides, the stimuli-responsive hydrogels, the conducting polymer hydrogels are discussed, with specific attention to the energy generation and storage behavior of the xerogel derived from the hydrogel. The electronic and ionic conducting gels have been discussed that have applications in various electronic devices, e.g., organic field effect transistors, soft robotics, ionic skins, and sensors. The properties of polymer hybrid gels containing carbon nanomaterials have been exemplified here giving attention to applications in supercapacitors, dye sensitized solar cells, photocurrent switching, etc. Recent trends in the properties and applications of some natural polymer gels to produce thermal and acoustic insulating materials, drug delivery vehicles, self-healing material, tissue engineering, etc., are discussed. Besides the polymer gels, peptide gels of different dipeptides, tripeptides, oligopeptides, polypeptides, cyclic peptides, etc., are discussed, giving attention mainly to biosensing, bioimaging, and drug delivery applications. The properties of peptide-based hybrid hydrogels with polymers, nanoparticles, nucleotides, fullerene, etc., are discussed, giving specific attention to drug delivery, cell culture, bio-sensing, and bioimaging properties. Thus, the present review delineates, in short, the preparation, properties, and applications of different polymer and peptide hydrogels prepared in the past few years.
在这篇综述中，我们重点关注聚合物水凝胶利用其不同的光电特性在靶向药物输送、组织工程和生物传感方面的刺激响应特性的最新进展。此外，还讨论了具有刺激响应性的水凝胶，特别是水凝胶衍生的干凝胶的能量产生和存储行为的导电聚合物水凝胶。讨论了电子和离子导电凝胶，它们在各种电子设备中的应用，例如有机场效应晶体管、软机器人、离子皮肤和传感器。本文举例说明了含有碳纳米材料的聚合物杂化凝胶的性质和应用，特别关注超级电容器、染料敏化太阳能电池、光电流开关等方面的应用。讨论了一些天然聚合物凝胶在制备热和声学绝缘材料、药物输送载体、自修复材料、组织工程等方面的最新发展趋势。除了聚合物凝胶外，还讨论了不同二肽、三肽、寡肽、多肽、环肽等肽凝胶，主要关注生物传感、生物成像和药物输送应用。讨论了基于肽的杂化水凝胶与聚合物、纳米粒子、核苷酸、富勒烯等的性质，特别关注药物输送、细胞培养、生物传感和生物成像性质。因此，本综述简要描述了过去几年中制备的不同聚合物和肽水凝胶的制备、性质和应用。
