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可靠的长期器官冷冻保存使供体器官库成为现实。

Reliable long-term organ cryopreservation makes donor organ bank a feasible reality.

出版信息

Artif Organs. 2023 Sep;47(9):1421-1422. doi: 10.1111/aor.14629. Epub 2023 Aug 11.

Abstract

Long-term donor organ preservation has been sought after since the beginning of transplantation. Static cold storage is the gold standard for organ transport but is limited to short-term preservation because of the inability to maintain subfreezing temperatures without harmful ice cyrstal formation. Recent developments in cryopreservation via vitrification and nanowarming have demonstrated reliable storage and restoration of healthy donor organs without ice crystallization.

摘要

自移植手术开展以来,人们一直在寻求长期的供体器官保存方法。静态低温冷藏是器官运输的金标准,但由于无法在不形成有害冰晶的情况下保持亚冷冻温度,因此其保存时间有限。通过玻璃化和纳米升温进行冷冻保存的最新发展已经证明,这种方法可以可靠地储存和恢复健康的供体器官,而不会形成冰晶。

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引用本文的文献

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