Department of Biomedical Sciences, Tropical Diseases Research Center, Ndola, Zambia.
Department of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka, Zambia.
J Vet Med Sci. 2023 Oct 19;85(10):1136-1141. doi: 10.1292/jvms.22-0565. Epub 2023 Aug 14.
We aimed to assess the proportion of tuberculosis in humans and tuberculosis (TB)-associated abattoir condemnations from the animal sector, as well as determine risk factors of zoonotic tuberculosis at the animal-human interface in Zambia. The study involved 255 presumptive TB patients and 156 cattle carcasses and was conducted from April 2020 to December 2021. Univariable and multivariable logistic regressions were performed for risk factor analysis for zoonotic TB. The overall proportion of bovine tuberculosis in traditional cattle and the proportion of tuberculosis among presumptive TB patients were 39.7% and 10.2%, respectively. Consumption of raw milk (adjusted odds ratio (AOR)=2.72, 95% confidence interval (CI): 1.73-4.28) and history of previous contact with a TB patient (AOR=1.86, 95% CI: 1.17-2.95) were risk factors for zoonotic TB at the animal-human interface of Zambia. Therefore, community campaigns and sensitization on zoonotic TB transmission are recommended.
我们旨在评估赞比亚人类结核病和与屠宰场相关的动物结核病（TB）淘汰比例，并确定动物-人类接触界面中动物源结核病的危险因素。该研究涉及 255 例疑似结核病患者和 156 头牛尸体，于 2020 年 4 月至 2021 年 12 月进行。采用单变量和多变量逻辑回归分析进行动物源结核病的危险因素分析。传统牛群中牛型结核的总体比例和疑似结核病患者中结核病的比例分别为 39.7%和 10.2%。食用生牛奶（调整后的优势比（AOR）=2.72，95%置信区间（CI）：1.73-4.28）和与 TB 患者有过接触史（AOR=1.86，95%CI：1.17-2.95）是赞比亚动物-人类接触界面中动物源结核病的危险因素。因此，建议开展社区宣传活动，提高对动物源结核病传播的认识。
