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除草剂苯磺隆甲酯通过阻断 OsCNGC12 通道中的钙离子流来抑制水稻幼苗的发育。

The herbicide bensulfuron-methyl inhibits rice seedling development by blocking calcium ion flux in the OsCNGC12 channel.

机构信息

National Key Laboratory of Green Pesticide/Key Laboratory of Natural Pesticide and Chemical Biology, Ministry of Education, South China Agricultural University, Guangzhou, 510642, China.

China National Tobacco Corporation Guangdong Branch, Guangzhou, 510642, China.

出版信息

Plant J. 2023 Dec;116(5):1218-1233. doi: 10.1111/tpj.16418. Epub 2023 Aug 14.

DOI:10.1111/tpj.16418
PMID:37574927
Abstract

Identification of translocator protein-related genes involved in bensulfuron-methyl (BSM) uptake and transport in rice could facilitate the development of herbicide-tolerant cultivars by inactivating them. This study found that the OsCNGC12 mutants not only reduced BSM uptake but also compromised the Ca ⁺ efflux caused by BSM in the roots, regulating dynamic equilibrium of Ca ⁺ inside the cell and conferring non-target-site tolerance to BSM.

摘要

鉴定与苯磺隆（BSM）在水稻中的吸收和转运有关的易位子蛋白相关基因，可通过使其失活来促进抗除草剂品种的开发。本研究发现，OsCNGC12 突变体不仅减少了 BSM 的吸收，而且削弱了 BSM 在根部引起的 Ca ⁺外排，调节了细胞内 Ca ⁺的动态平衡，并赋予了 BSM 的非靶标位点耐受性。

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