Asif Abrar, Afzaal Muhammad, Shahid Hina, Saeed Farhan, Ahmed Aftab, Shah Yasir Abbas, Ejaz Afaf, Ghani Samia, Ateeq Huda, Khan Mahbubur Rahman
Food Safety and Biotechnology Lab, Department of Food Science Government College University Faisalabad Faisalabad Pakistan.
Women Medical Officer District Head Quarters (DHQ) Hospital Vehari Vehari Pakistan.
Food Sci Nutr. 2023 Jun 6;11(8):4472-4484. doi: 10.1002/fsn3.3465. eCollection 2023 Aug.
Functional foods are gaining significant research attention of researchers due to their health-endorsing properties due to their bioactive components either living cells (probiotics) or nonviable cells (prebiotics). The term "postbiotic" specifies the soluble substances, such as enzymes, peptides, teichoic acids, muropeptides derived from peptidoglycans, polysaccharides, cell surface proteins, and organic acids, that are secreted by living bacteria or released after bacterial lysis. Due to various signaling molecules which may have antioxidant, immunomodulatory, antiinflammatory, antihypertensive, and antiproliferative activities, postbiotics offer great potential to be used in pharmaceutical, food, and nutraceutical industries, to promote health and ailment prevention. This recent review is a landmark of information relevant to the production of postbiotics along with salient features to use in various fields ranging from food to immunomodulation and selective and effective therapy. It also puts forward the concept that postbiotics are way more effective than probiotics in the veterinary, food as well as medical field which ultimately helps in reducing the disease burden along with human health.
功能性食品因其生物活性成分(活细胞(益生菌)或非活细胞(益生元))具有促进健康的特性而受到研究人员的广泛关注。“后生元”一词指的是由活细菌分泌或细菌裂解后释放的可溶性物质,如酶、肽、磷壁酸、源自肽聚糖的胞壁肽、多糖、细胞表面蛋白和有机酸。由于各种可能具有抗氧化、免疫调节、抗炎、降压和抗增殖活性的信号分子,后生元在制药、食品和营养保健品行业具有巨大的应用潜力,可促进健康和预防疾病。这篇最新综述是与后生元生产相关信息的一个里程碑,同时还介绍了后生元在从食品到免疫调节以及选择性有效治疗等各个领域的显著应用特点。它还提出了后生元在兽医、食品以及医学领域比益生菌更有效的概念,这最终有助于减轻疾病负担并促进人类健康。