Pan Su-Fei, Huang Shi-Mei, Xie Lian, Zhang Yuan-Yuan, Tang Yu-Rong, Wang Xiao-Zhen
Department of Clinical Laboratory, Shengli Oilfield Central Hospital, Dongying, People's Republic of China.
Infect Drug Resist. 2023 Aug 8;16:5085-5090. doi: 10.2147/IDR.S420991. eCollection 2023.
() is typically reported to be involved in superficial and subcutaneous fungal infections but overlooked in invasive infections, which is associated with a high mortality rate. It poses a diagnostic challenge due to its confusable characteristics to other hyaline hyphomycetes. Here, we reported a psoriasis patient with an invasive infection. The patient presents an abscess at the intermuscular space of the left hip and an increased C-reactive protein level. Pus culture showed white-greyish, cottonlike colonies with aerial mycelium and terminal oval conidia, suggesting . This rare fungus was rapidly confirmed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and RNA sequencing. The patient was successfully treated with voriconazole with no recurrence of the abscesses despite delayed treatment. This is the first such case infection report from China that described an unusual case of intermuscular space abscesses due to . This report highlights the possibility of fungal infections in deeper tissue, as well as the necessity of thorough evaluation and microbiological diagnosis for invasive infections, particularly in immunocompromised patients.
（）通常被报道与浅表和皮下真菌感染有关，但在侵袭性感染中被忽视，而侵袭性感染与高死亡率相关。由于它与其他透明丝孢菌的特征易混淆，因此带来了诊断挑战。在此，我们报告了一名患有侵袭性感染的银屑病患者。该患者左髋部肌间隙出现脓肿，C反应蛋白水平升高。脓液培养显示出灰白色、棉絮状菌落，带有气生菌丝和末端椭圆形分生孢子，提示（此处原文不完整，无法准确翻译相关内容）。这种罕见真菌通过基质辅助激光解吸电离飞行时间质谱和RNA测序迅速得到确诊。尽管治疗延迟，但患者接受伏立康唑治疗后成功治愈，脓肿未复发。这是中国首例此类感染报告，描述了由（此处原文不完整，无法准确翻译相关内容）引起的肌间隙脓肿不寻常病例。本报告强调了深部组织真菌感染的可能性，以及对侵袭性感染进行全面评估和微生物学诊断的必要性，特别是在免疫功能低下的患者中。
