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伏立康唑和特比萘芬成功治疗真菌血症。

fungemia successfully treated with voriconazole and terbinafine.

作者信息

Jabr Ra'ed, Hammoud Kassem

机构信息

Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA.

Division of Infectious Diseases, University of Kansas Medical Center, Kansas City, KS 66160, USA.

出版信息

IDCases. 2020 Aug 8;22:e00928. doi: 10.1016/j.idcr.2020.e00928. eCollection 2020.

DOI:10.1016/j.idcr.2020.e00928
PMID:32884903
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7452905/
Abstract

is ubiquitous in the environment and is considered an emerging infection. Immunocompromised hosts can have a wide spectrum of diseases ranging from cutaneous to disseminated disease that may involve pulmonary, central nervous system, or bone. Disseminated disease in immunocompetent hosts is uncommon. Treatment of deep-seated infections is challenging because of the limited susceptibility of the species to all current antifungal drugs. We report a case of fungemia with a presumed pulmonary involvement in an immunocompetent patient. The fungemia was successfully treated with oral voriconazole and terbinafine.

摘要

在环境中普遍存在，被认为是一种新发感染。免疫功能低下的宿主可出现从皮肤感染到播散性疾病等广泛的疾病，可能累及肺部、中枢神经系统或骨骼。免疫功能正常的宿主发生播散性疾病并不常见。由于该菌种对目前所有抗真菌药物的敏感性有限，深部感染的治疗具有挑战性。我们报告一例免疫功能正常患者发生的真菌血症，推测伴有肺部受累。该真菌血症通过口服伏立康唑和特比萘芬成功治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e090/7452905/a4b59b792878/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e090/7452905/f09f7e3001d5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e090/7452905/a4b59b792878/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e090/7452905/f09f7e3001d5/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e090/7452905/a4b59b792878/gr2.jpg

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