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术前睡眠和疼痛行为可预测全膝关节置换术后的失眠症状和疼痛:一项为期 12 个月的纵向观察研究。

Presurgical sleep and pain behaviors predict insomnia symptoms and pain after total knee arthroplasty: a 12-month longitudinal, observational study.

机构信息

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21224, United States.

Edson College of Nursing and Health Innovation, Arizona State University, Phoenix, AZ 85004, United States.

出版信息

Pain Med. 2023 Nov 2;24(11):1224-1233. doi: 10.1093/pm/pnad106.

Abstract

OBJECTIVE

Up to 40% of individuals who undergo total knee arthroplasty (TKA) experience some degree of pain following surgery. Presurgical insomnia has been identified as a predictor of postsurgical pain; however, modifiable presurgical behaviors related to insomnia have received minimal attention. The objective of the present study was to develop a 2-item sleep and pain behavior scale (SP2) to investigate a maladaptive sleep and pain behavior and is a secondary analysis of a larger, parent study.

METHODS

Patients (N = 109) completed SP2 at baseline and 12 months and questionnaires assessing sleep and pain at baseline (pre-TKA), 6 weeks, 3, 6, and 12 months post-TKA. SP2 demonstrated adequate preliminary psychometric properties.

RESULTS

As hypothesized, even after controlling for baseline insomnia, pain, anxiety and other covariates, baseline SP2 predicted insomnia symptom severity at 6 weeks (β = 2.828), 3 (β = 2.140), 6 (β = 2.962), and 12 months (β = 1.835) and pain at 6 weeks (β = 6.722), 3 (β = 5.536), and 6 months (β = 7.677) post-TKA (P < .05). Insomnia symptoms at 6-weeks post-TKA mediated the effect of presurgical SP2 on pain at 3 (95% CI: 0.024-7.054), 6 (95%CI: 0.495-5.243), and 12 months (95% CI: 0.077-2.684).

CONCLUSIONS

This provides preliminary evidence that patients who cope with pain by retiring to their bed and bedroom have higher rates of post-surgical insomnia and pain and supports efforts to target this maladaptive sleep and pain behavior to reduce postsurgical pain.

摘要

目的

接受全膝关节置换术(TKA)的患者中有 40%在术后会经历不同程度的疼痛。术前失眠已被确定为术后疼痛的预测因素;然而,与失眠相关的可改变的术前行为受到的关注很少。本研究的目的是开发一个 2 项睡眠和疼痛行为量表(SP2),以调查一种适应不良的睡眠和疼痛行为,这是对更大的母研究的二次分析。

方法

患者(N=109)在基线和 12 个月时完成 SP2,并在基线(TKA 前)、6 周、3、6 和 12 个月时完成睡眠和疼痛问卷。SP2 显示出足够的初步心理测量学特性。

结果

正如假设的那样,即使在控制了基线时的失眠、疼痛、焦虑和其他协变量后,基线 SP2 仍预测了 6 周(β=2.828)、3 周(β=2.140)、6 周(β=2.962)和 12 个月(β=1.835)时的失眠症状严重程度,以及 6 周(β=6.722)、3 周(β=5.536)和 6 个月(β=7.677)时的疼痛(P<0.05)。TKA 后 6 周的失眠症状中介了术前 SP2 对 3 周(95%CI:0.024-7.054)、6 周(95%CI:0.495-5.243)和 12 个月(95%CI:0.077-2.684)时疼痛的影响。

结论

这初步证明了通过卧床和卧室来应对疼痛的患者术后失眠和疼痛的发生率更高,并支持努力针对这种适应不良的睡眠和疼痛行为进行治疗,以减轻术后疼痛。

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